globalchange  > 气候变化与战略
CSCD ID: CSCD:5615118
Title:
基于系统生物学和合成生物学的重要平台化学品生物制造的研究进展
Alternative Title: Advances in production of important platform chemicals by bio-manufacturing based on systems biology and synthetic biology
Author: 袁海波; 李江华; 刘龙; 堵国成; 陈坚
Source Publication: 化工学报
ISSN: 0438-1157
Publishing Year: 2016
Volume: 67, Issue:1, Pages:219-224,232
Language: 中文
keyword in Chinese: 系统生物学 ; 合成生物学 ; 生物催化 ; 生物技术 ; 平台化合物 ; 生物制造
Keyword: systems biology ; synthetic biology ; biocatalysis ; biotechnology ; platform chemical ; bio-manufacture
WOS Category: BIOTECHNOLOGY APPLIED MICROBIOLOGY
WOS Research Area: Biotechnology & Applied Microbiology
Abstract: 基于生物质资源的平台化学品制造,是解决目前石化资源枯竭和环境问题的重要措施,对经济社会的可持续发展具有重要意义。本文主要介绍了系统生物学和合成生物学在有机酸(琥珀酸、富马酸、L-苹果酸、葡萄糖二酸、丙酮酸、苯丙酮酸、alpha-酮戊二酸)以及其他平台化学品(2,5-呋喃二甲酸)生物制造中的应用,并展望了生物制造在平台化学品生产中的未来发展方向。
English Abstract: Due to the limited amount of fossil fuels and global warming problem, bio-manufacturing based on renewable biomass has been paid more attention. In this review, the contribution of systems biology and synthetic biology in bio-manufacture of platform chemicals like organic acid such as succinate, fumarate, malate, glucaric acid, pyruvate, phenylpyruvic acid, alpha-ketoglutarate and other platform chemicals such as 2,5-furandicarboxylic acid are reviewed. Finally, the trends of bio-manufacture for platform chemical are prospected.
Document Type: 期刊论文
Identifier: http://119.78.100.158/handle/2HF3EXSE/150978
Appears in Collections:气候变化与战略

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Affiliation: 江南大学生物工程学院, 无锡, 江苏 214122, 中国

Recommended Citation:
袁海波,李江华,刘龙,等. 基于系统生物学和合成生物学的重要平台化学品生物制造的研究进展[J]. 化工学报,2016-01-01,67(1):219-224,232
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