DOI: 10.1016/j.marpolbul.2017.11.062
论文题名: Dioxin-like compounds bioavailability and genotoxicity assessment in the Gulf of Follonica, Tuscany (Northern Tyrrhenian Sea)
作者: Guidi P. ; Corsolini S. ; Bernardeschi M. ; Rocco L. ; Nigro M. ; Baroni D. ; Mottola F. ; Scarcelli V. ; Santonastaso M. ; Falleni A. ; Della Torre C. ; Corsi I. ; Pozo K. ; Frenzilli G.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
出版年: 2018
卷: 126 起始页码: 467
结束页码: 472
语种: 英语
Scopus关键词: Biochemistry
; Hydraulic structures
; Organic pollutants
; Polychlorinated biphenyls
; Coastal marine environment
; DNA damages
; Genomic template stability
; Mytilus galloprovincialis
; PCDDs/DFs
; RAPD-PCR
; TEQs
; Toxic Equivalents TEQ
; Polymerase chain reaction
; dioxin
; polychlorinated dibenzodioxin
; polychlorinated dibenzofuran
; bioassay
; bioavailability
; chemical pollutant
; DNA
; environmental assessment
; genotoxicity
; marine pollution
; mining
; PCB
; PCDD
; PCDF
; polymerase chain reaction
; seafood
; animal cell
; animal experiment
; animal tissue
; Article
; bioaccumulation
; coastal waters
; comet assay
; concentration (parameters)
; controlled study
; DNA damage
; DNA template
; dry weight
; genomic instability
; genotoxicity
; gill
; Gulf of Follonica
; Italy
; limit of detection
; limit of quantitation
; micronucleus
; micronucleus test
; Mytilus galloprovincialis
; nonhuman
; oceanic regions
; polymerase chain reaction
; random amplified polymorphic DNA
; waste water
; Italy
; Mediterranean Sea
; Tuscany
; Tyrrhenian Sea
; Mytilus galloprovincialis
英文摘要: The Gulf of Follonica (Italy) is impacted by the chemical pollution from ancient mining activity and present industrial processes. This study was aimed to determine the bioavailability of dioxin-like compounds (DLCs) in coastal marine environment and to assess the genotoxic potential of waste waters entering the sea from an industrial canal. Moderately high levels of DCLs compounds (∑ PCDDs + PCDFs 2.18–29.00 pg/g dry wt) were detected in Mytilus galloprovincialis transplanted near the waste waters canal and their corresponding Toxic Equivalents (TEQs) calculated. In situ exposed mussels did not show any genotoxic effect (by Comet and Micronucleus assay). Otherwise, laboratory exposure to canal waters exhibited a reduced genomic template stability (by RAPD-PCR assay) but not DNA or chromosomal damage. Our data reveal the need to focus on the levels and distribution of DLCs in edible species from the study area considering their potential transfer to humans through the consumption of sea food. © 2017 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/106933
Appears in Collections: 气候减缓与适应 科学计划与规划
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作者单位: Department of Clinical and Experimental Medicine – Section of Applied Biology and Genetics, University of Pisa, Pisa, Italy; Department of Physical, Earth and Environmental Sciences, University of Siena, Siena, Italy; Department of Environmental, Biological and Pharmaceutical, Sciences and Technologies, Second University of Naples, Caserta, Italy; Department of Biosciences, University of Milan, Milan, Italy; Masaryk University, Research Centre for Toxic Compounds in the Environment, Brno, Czech Republic; Facultad de Ciencias, Universidad Católica Santísima Concepción, Concepción, Chile
Recommended Citation:
Guidi P.,Corsolini S.,Bernardeschi M.,et al. Dioxin-like compounds bioavailability and genotoxicity assessment in the Gulf of Follonica, Tuscany (Northern Tyrrhenian Sea)[J]. Marine Pollution Bulletin,2018-01-01,126