DOI: 10.1016/j.watres.2018.08.026
Scopus记录号: 2-s2.0-85053063618
论文题名: Oxidation of fluoroquinolone antibiotics by peroxymonosulfate without activation: Kinetics, products, and antibacterial deactivation
作者: Zhou Y. ; Gao Y. ; Pang S.-Y. ; Jiang J. ; Yang Y. ; Ma J. ; Yang Y. ; Duan J. ; Guo Q.
刊名: Water Research
ISSN: 431354
出版年: 2018
卷: 145 起始页码: 210
结束页码: 219
语种: 英语
英文关键词: Antibacterial deactivation
; Fluoroquinolone antibiotics
; Oxidation kinetics
; Oxidation products
; Peroxymonosulfate
Scopus关键词: Amines
; Antibiotics
; Association reactions
; Degradation
; Escherichia coli
; Free radical reactions
; High performance liquid chromatography
; Ionization of liquids
; Kinetics
; Oxidation
; Rate constants
; Sulfur compounds
; Water treatment
; Water wells
; Antibacterial deactivation
; Fluoroquinolone antibiotics
; Oxidation kinetics
; Oxidation products
; Peroxymonosulfate
; Surface waters
; antibiotics
; antimicrobial activity
; degradation
; detection method
; hydroxyl radical
; inhibition
; organic compound
; oxidant
; oxidation
; ozone
; pH
; reaction kinetics
; surface water
; Bacteria (microorganisms)
; Escherichia coli
英文摘要: While fluoroquinolone (FQ) antibiotics are susceptible to degradation by sulfate and/or hydroxyl radicals formed in peroxymonosulfate (PMS) based advanced oxidation processes, here we report that unactivated PMS itself exhibits a specific high reactivity toward FQs for the first time. Reaction kinetics of PMS with two model FQs, ciprofloxacin (CF) and enrofloxacin (EF), showed a strong pH dependency with apparent second-order rate constants of 0.10–13.05 M−1s−1 for CF and 0.51–33.17 M−1s−1 for EF at pH 5–10. This pH dependency was well described by species-specific parallel reactions. On the basis of reaction kinetics and structure–activity assessment, the tertiary and secondary aliphatic N4 amines on the FQs’ piperazine ring were proposed to be the main reaction sites. High performance liquid chromatography/electrospray ionization tandem mass analysis showed the formation of hydroxylated, N-oxide, and dealkylated products. Bacterial growth inhibition bioassays using Escherichia coli showed that oxidation products of FQs by PMS retained negligible antibacterial potency in comparison to parent FQs. Kinetic modeling using the rate constants estimated from pure water well predicted the oxidation kinetics of low levels of CF and EF by PMS in surface water. The degradation efficiency of FQs by PMS in surface water was slightly lower than that by ozone, comparable to that by ferrate, and much higher than that by permanganate. These results suggest that PMS is a promising oxidant for the treatment of FQs in water. © 2018 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/112412
Appears in Collections: 气候减缓与适应
There are no files associated with this item.
作者单位: State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin, 150090, China; School of Municipal and Environmental Engineering, Jilin Jianzhu University, Changchun, 130118, China; College of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin, 150040, China
Recommended Citation:
Zhou Y.,Gao Y.,Pang S.-Y.,et al. Oxidation of fluoroquinolone antibiotics by peroxymonosulfate without activation: Kinetics, products, and antibacterial deactivation[J]. Water Research,2018-01-01,145