globalchange  > 气候减缓与适应
DOI: 10.1016/j.watres.2018.07.014
Scopus记录号: 2-s2.0-85053034586
论文题名:
Exposure to solar light reduces cytotoxicity of sewage effluents to mammalian cells: Roles of reactive oxygen and nitrogen species
作者: Du Y.; Wu Q.-Y.; Lv X.-T.; Wang Q.-P.; Lu Y.; Hu H.-Y.
刊名: Water Research
ISSN: 431354
出版年: 2018
卷: 143
起始页码: 570
结束页码: 578
语种: 英语
英文关键词: Cytotoxicity ; Reactive nitrogen species ; Reactive oxygen species ; Sewage effluents ; Solar irradiation
Scopus关键词: Cells ; Cytology ; Cytotoxicity ; Detoxification ; Irradiation ; Lake pollution ; Mammals ; Nitrogen ; Potable water ; River pollution ; Sewage ; Water quality ; Chinese Hamster ovary cells ; Detoxification mechanism ; Natural environments ; Reactive nitrogen species ; Reactive oxygen and nitrogen species ; Reactive oxygen species ; Sewage effluents ; Solar irradiation ; Effluents ; cell component ; chemical pollutant ; detoxification ; discharge ; drinking water ; effluent ; nitrogen ; reactive oxygen species ; reduction ; solar radiation ; toxicity ; water quality ; Cricetulus griseus ; Mammalia
英文摘要: Sewage effluents can contain hundreds of toxic pollutants, making them a risk to humans when involved in drinking water. It is therefore important to evaluate the cytotoxicity of sewage effluents to mammalian cells. Solar light might influence the water quality of sewage effluents after their discharge into lakes or rivers, altering their cytotoxicity. In this study, natural solar light was found to lower the cytotoxicity of sewage effluents to Chinese hamster ovary (CHO) cells. Cytotoxicity of different samples decreased by 31%–65% after 12 h of simulated irradiation. Ultraviolet in sunlight was the major contributor to the cytotoxicity reduction. Aquatic reactive oxygen species (ROS), including singlet oxygen, superoxide anions, hydrogen peroxide, and hydroxyl radicals, were generated in the effluents under irradiation and they contributed to part of cytotoxicity reduction. Pollutants in sewage effluents induced cytotoxicity by simultaneously elevating the levels of intracellular ROS and intracellular reactive nitrogen species (RNS) in CHO cells. Solar light and the aquatic ROS formed under irradiation reduced the cytotoxicity because the transformed pollutants in sewage effluents increased lower intracellular ROS and RNS levels. These results help reveal the detoxification mechanism of sewage effluents in natural environment. © 2018 Elsevier Ltd
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/112565
Appears in Collections:气候减缓与适应

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作者单位: Key Laboratory of Microorganism Application and Risk Control of Shenzhen, Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental Safety, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China; Environmental Simulation and Pollution Control State Key Joint Laboratory, State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC), School of Environment, Tsinghua University, Beijing, 100084, China; Shenzhen Environmental Science and New Energy Technology Engineering Laboratory, Tsinghua-Berkeley Institute, Shenzhen, 518055, China; Division of Energy and Environment, Graduate School at Shenzhen, Tsinghua University, Room 1810, Shenzhen, 518055, China

Recommended Citation:
Du Y.,Wu Q.-Y.,Lv X.-T.,et al. Exposure to solar light reduces cytotoxicity of sewage effluents to mammalian cells: Roles of reactive oxygen and nitrogen species[J]. Water Research,2018-01-01,143
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