DOI: 10.1016/j.watres.2018.05.016
Scopus记录号: 2-s2.0-85054453038
论文题名: Occurrence, genotyping, and health risk of Cryptosporidium and Giardia in recreational lakes in Tianjin, China
作者: Xiao S. ; Yin P. ; Zhang Y. ; Zhao X. ; Sun L. ; Yuan H. ; Lu J. ; Hu S.
刊名: Water research
ISSN: 18792448
出版年: 2018
卷: 141 起始页码: 46
结束页码: 56
语种: 英语
英文关键词: Cryptosporidium
; Genotyping
; Giardia
; Quantitative microbial risk assessment (QMRA)
; Recreational water
Scopus关键词: adolescent
; adult
; aged
; child
; China
; cryptosporidiosis
; Cryptosporidium
; female
; genetics
; genotype
; Giardia
; giardiasis
; human
; infant
; isolation and purification
; lake
; male
; microbiology
; middle aged
; newborn
; oocyst
; preschool child
; recreation
; risk assessment
; very elderly
; young adult
; Adolescent
; Adult
; Aged
; Aged, 80 and over
; Child
; Child, Preschool
; China
; Cryptosporidiosis
; Cryptosporidium
; Female
; Genotype
; Giardia
; Giardiasis
; Humans
; Infant
; Infant, Newborn
; Lakes
; Male
; Middle Aged
; Oocysts
; Recreation
; Risk Assessment
; Young Adult
英文摘要: Cryptosporidium and Giardia are critical parasites in the etiology of diarrhea worldwide, and often cause waterborne outbreaks. The presence of Cryptosporidium and Giardia in recreational lakes was investigated with molecular characterization, and a comprehensive quantitative microbial risk assessment (QMRA) of protozoan infections was performed, considering multiple exposure pathways, differences in age, sex, and disease severity, and the genotypes of the protozoa. Forty-three (82.7%) and 51 (98.1%) water samples were positive for Cryptosporidium oocysts and Giardia cysts, respectively, with average counts of 3.65 oocysts/10 L and 12.58 cysts/10 L, respectively. Six Cryptosporidium species and three Giardia lamblia assemblages were confirmed with molecular analyses. The protozoan concentration was significantly associated with water turbidity, but not with the total coliform numbers. Swimming in the lakes entailed the highest incidence risk of 5.72 × 10-4 per person per year (pppy) (95% confidence interval (CI): 0.03-43.33 × 10-4) for Cryptosporidium and 4.04 × 10-4 pppy (95% CI: 0.01-32.66 × 10-4) for Giardia, whereas wading entailed the lowest risk (2.20 × 10-4 and 1.70 × 10-4 pppy, respectively). The annual burdens attributable to recreational-water-associated cryptosporidiosis and giardiasis were 3.44 (95% CI: 0.04-23.51) and 1.81 (95% CI: 0.01-12.96) disability-adjusted life years per 1,000,000 individuals per year, respectively. Children were more likely to have an individual disease burden than adults, and males were more likely than females. Sensitivity analysis highlighted the great importance of controlling the proportion of exposed individuals and reducing the frequency of exposure. The methodology and results of this study will allow us to better evaluate and reduce the burden of Cryptosporidium and/or Giardia infections associated with recreational water use in China and other countries. Copyright © 2018 Elsevier Ltd. All rights reserved. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/112660
Appears in Collections: 气候减缓与适应
There are no files associated with this item.
作者单位: School of Environmental and Municipal Engineering, Tianjin Chengjian University, Tianjin 300384, PR China; Tianjin Key Laboratory of Aquatic Science and Technology, Tianjin 300384, PR China; School of Environmental and Municipal Engineering, Tianjin Chengjian University, Tianjin, 300384, China; School of Medicine, Nankai University, Tianjin, 300071, China
Recommended Citation:
Xiao S.,Yin P.,Zhang Y.,et al. Occurrence, genotyping, and health risk of Cryptosporidium and Giardia in recreational lakes in Tianjin, China[J]. Water research,2018-01-01,141