globalchange  > 气候减缓与适应
DOI: 10.1016/j.watres.2018.02.036
Scopus ID: 2-s2.0-85042685774
Chlorine disinfection increases both intracellular and extracellular antibiotic resistance genes in a full-scale wastewater treatment plant
Author: Liu S.-S.; Qu H.-M.; Yang D.; Hu H.; Liu W.-L.; Qiu Z.-G.; Hou A.-M.; Guo J.; Li J.-W.; Shen Z.-Q.; Jin M.
Source Publication: Water Research
ISSN: 431354
Publishing Year: 2018
Volume: 136
pages begin: 131
pages end: 136
Language: 英语
Keyword: Antibiotic resistance genes (ARGs) ; Antibiotic resistant bacteria (ARB) ; Chlorination ; Disinfection ; Extracellular ARGs (eARGs) ; Intracellular ARGs (iARGs)
Scopus Keyword: Antibiotics ; Chemicals removal (water treatment) ; Chlorination ; Disinfection ; Effluent treatment ; Effluents ; Enzyme activity ; Escherichia coli ; Genes ; Health risks ; Sewage pumping plants ; Sulfur compounds ; Toxicity ; Water treatment plants ; Ammonium concentrations ; Antibiotic resistance genes ; Antibiotic-resistant bacteria ; Chlorine disinfection ; Extracellular ; Intracellular ARGs (iARGs) ; Urban wastewater treatment plants ; Wastewater treatment plants ; Wastewater treatment ; aminoglycoside ; ammonia ; beta lactam ; chlorine ; chlorine dioxide ; macrolide ; rifampicin ; sulfonamide ; tetracycline ; vancomycin ; antiinfective agent ; chlorine ; disinfectant agent ; Escherichia coli protein ; antibiotic resistance ; antibiotics ; bacterium ; chlorination ; chlorine ; concentration (composition) ; disinfection ; gene ; low temperature ; risk assessment ; temperature effect ; wastewater treatment plant ; antibiotic resistance ; Article ; chlorination ; controlled study ; disinfection ; environmental factor ; Escherichia coli ; gene dosage ; gene frequency ; nonhuman ; priority journal ; real time polymerase chain reaction ; waste water treatment plant ; disinfection ; drug effect ; genetics ; halogenation ; metabolism ; microbiology ; waste water ; water management ; Escherichia coli ; Anti-Bacterial Agents ; Chlorine ; Disinfectants ; Disinfection ; Drug Resistance, Bacterial ; Drug Resistance, Microbial ; Escherichia coli ; Escherichia coli Proteins ; Halogenation ; Tetracycline ; Waste Water ; Water Purification
English Abstract: The emergence and spread of antibiotic resistance has posed a major threat to both human health and environmental ecosystem. Although the disinfection has been proved to be efficient to control the occurrence of pathogens, little effort is dedicated to revealing potential impacts of disinfection on transmission of antibiotic resistance genes (ARGs), particularly for free-living ARGs in final disinfected effluent of urban wastewater treatment plants (UWWTP). Here, we investigated the effects of chlorine disinfection on the occurrence and concentration of both extracellular ARGs (eARGs) and intracellular ARGs (iARGs) in a full-scale UWWTP over a year. We reported that the concentrations of both eARGs and iARGs would be increased by the disinfection with chlorine dioxide (ClO2). Specifically, chlorination preferentially increased the abundances of eARGs against macrolide (ermB), tetracycline (tetA, tetB and tetC), sulfonamide (sul1, sul2 and sul3), β-lactam (ampC), aminoglycosides (aph(2’)-Id), rifampicin (katG) and vancomycin (vanA) up to 3.8 folds. Similarly, the abundances of iARGs were also increased up to 7.8 folds after chlorination. In terms of correlation analyses, the abundance of Escherichia coli before chlorination showed a strong positive correlation with the total eARG concentration, while lower temperature and higher ammonium concentration were assumed to be associated with the concentration of iARGs. This study suggests the chlorine disinfection could increase the abundances of both iARGs and eARGs, thereby posing risk of the dissemination of antibiotic resistance in environments. © 2018 Elsevier Ltd
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被引频次[WOS]:75   [查看WOS记录]     [查看WOS中相关记录]
Document Type: 期刊论文
Appears in Collections:气候减缓与适应

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Affiliation: Department of Environment and Health, Tianjin Institute of Environmental & Operational Medicine, Key Laboratory of Risk Assessment and Control for Environment & Food Safety, Tianjin, 300050, China; College of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China; Advanced Water Management Centre (AWMC), The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia

Recommended Citation:
Liu S.-S.,Qu H.-M.,Yang D.,et al. Chlorine disinfection increases both intracellular and extracellular antibiotic resistance genes in a full-scale wastewater treatment plant[J]. Water Research,2018-01-01,136
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