DOI: 10.1016/j.watres.2018.12.013
Scopus记录号: 2-s2.0-85059130852
论文题名: Sunlight driven photolytic ozonation as an advanced oxidation process in the oxidation of bezafibrate, cotinine and iopamidol
作者: Rivas F.J. ; Solís R.R. ; Beltrán F.J. ; Gimeno O.
刊名: Water Research
ISSN: 431354
出版年: 2019
起始页码: 226
结束页码: 242
语种: 英语
英文关键词: Bezafibrate
; Cotinine
; Iopamidol
; Ozone
; Sunlight radiation
Scopus关键词: Amides
; Oxidation
; Ozonization
; Radiation effects
; Toxicity
; Advanced Oxidation Processes
; Beneficial effects
; Bezafibrate
; Cotinine
; Iopamidol
; Recalcitrant compounds
; Sunlight radiation
; Transformation products
; Ozone
; alcohol
; amide
; amine
; bezafibrate
; cotinine
; iopamidol
; ozone
; chemical compound
; crustacean
; ecotoxicology
; experimental study
; ozonation
; photolysis
; photooxidation
; solar radiation
; Article
; controlled study
; Daphnia magna
; hydroxylation
; mineralization
; nonhuman
; oxidation
; ozonation
; photolysis
; priority journal
; quantitative structure activity relation
; sunlight
; survival
; Daphnia magna
英文摘要: This study investigates the efficacy of the system O3/sunlight radiation compared to dark ozonation when treating pharmaceuticals compounds of different reactivity, namely bezafibrate, cotinine, and iopamidol. Results show the beneficial effects of simulated sunlight radiation (300–800 nm) when treating ozone recalcitrant compounds such as cotinine and iopamidol. The system O3/sunlight radiation increased mineralization extent in all cases if compared to dark ozonation. Transformation products identified in individual runs suggest that amine oxidation and further alkyl chain attack is the main route of bezafibrate ozonation. Hydroxylation seems to be the preferential path in cotinine abatement while H abstraction from alcoholic moieties is suggested in the case of iopamidol. Toxicity of intermediates was approximately evaluated by QSAR methodologies and experimentally through Daphnia Magna survival after 24 h. As a rule of thumb, initial intermediates generated are even more toxic than parent compounds, however, after 120 min of treatment, toxicity significantly decreased. Amongst the most toxic compounds generated: 4-Chlorobenzoyltyramine, and 4-Chloro-N-[2-(3,4-dihydroxy-phenyl)-ethyl]-benzamide (from bezafibrate), and N-(2-Hydroxy-1-hydroxymethyl-ethyl)-N'-(1-hydroxymethyl-2-oxo-ethyl)-5-(2-hydroxy-propionylamino)-2,4,6-triiodo-isophthalamide, N,N′-Bis-(1-hydroxymethyl-2-oxo-ethyl)-5-(2-hydroxy-propionylamino)-2,4,6-triiodo-isophthalamide, and N-(1-Hydroxymethyl-2-oxo-ethyl)-5-(2-hydroxy-propionylamino)-2,4,6-triiodo-isophthalamide (from iopamidol) were identified. © 2018 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/122056
Appears in Collections: 气候变化事实与影响
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作者单位: Departamento de Ingeniería Química y Química Física, Universidad de Extremadura, Avda. Elvas s/n, Badajoz, 06006, Spain; Instituto Universitario del Agua, Cambio Climático y Sostenibilidad (IACYS), Universidad de Extremadura, Avda. de la Investigación s/n, Badajoz, 06006, Spain
Recommended Citation:
Rivas F.J.,Solís R.R.,Beltrán F.J.,et al. Sunlight driven photolytic ozonation as an advanced oxidation process in the oxidation of bezafibrate, cotinine and iopamidol[J]. Water Research,2019-01-01