globalchange  > 气候变化事实与影响
DOI: 10.1016/j.watres.2018.11.007
Scopus记录号: 2-s2.0-85056476483
论文题名:
High-throughput profiling of antibiotic resistance gene dynamic in a drinking water river-reservoir system
作者: Chen Y.; Su J.-Q.; Zhang J.; Li P.; Chen H.; Zhang B.; Gin K.Y.-H.; He Y.
刊名: Water Research
ISSN: 431354
出版年: 2019
起始页码: 179
结束页码: 189
语种: 英语
英文关键词: Antibiotic resistance genes ; Environmental gradient ; High-throughput qPCR ; River-reservoir system ; Structural equation model
Scopus关键词: Antibiotics ; Bacteria ; Behavioral research ; Dynamics ; Genes ; Polymerase chain reaction ; Population distribution ; Potable water ; Rain ; Rivers ; Telecommunication services ; Throughput ; Antibiotic resistance genes ; Environmental gradient ; High throughput ; River reservoirs ; Structural equation modeling ; Reservoirs (water) ; drinking water ; rain ; abundance ; antibiotic resistance ; drinking water ; environmental gradient ; gene ; model ; polymerase chain reaction ; reservoir ; river ; river basin ; runoff ; species diversity ; antibiotic resistance ; Article ; bacterial gene ; biomass ; microbial community ; priority journal ; river ; runoff ; scanning electron microscopy ; seasonal variation ; water supply ; Bacteria (microorganisms)
英文摘要: The rapid construction of reservoir in river basin generates a river-reservoir system containing an environmental gradient from river system to reservoir system in modern aquatic environment worldwide. Profiles of antibiotic resistance genes (ARGs) in river-reservoir system is essential to better understand their dynamic mechanisms in aquatic eco-environment. In this study, we investigated the diversity, abundance, distribution of ARGs and mobile genetic elements (MGEs) in a representative river-reservoir system using high-throughput quantitative PCR, as well as ranked the factors (e.g. antibiotics, bacterial biomass, bacteria communities, and MGEs) influencing the patterns of ARGs based on structural equation models (SEMs). Seasonal variations in absolute abundance of ARGs and MGEs exhibited similar trends with local rainfall, suggesting that seasonal runoff induced by the rainfall potentially promote the absolute abundance of ARGs and MGEs. In contrast, environmental gradient played more important roles in the detected number, relative abundance, distribution pattern of ARGs and MGEs in the river-reservoir system. Moreover, environmental gradient also made the co-occurrence patterns associated with ARGs subtypes, MGEs and bacteria genera in river system different from those in reservoir system. The SEMs revealed that MGEs contributed the most to shape the ARG profiles. Overall, our findings provide novel insights into the mechanisms of environmental gradient on ARGs dynamics in river-reservoir system, probably via influencing the MGEs, antibiotics, pathogenic bacteria community and nonpathogenic bacteria community. © 2018 Elsevier Ltd
Citation statistics:
被引频次[WOS]:138   [查看WOS记录]     [查看WOS中相关记录]
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/122161
Appears in Collections:气候变化事实与影响

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作者单位: School of Environmental Science and Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China; School of Environment and Energy Engineering, Anhui Jianzhu University, Hefei, Anhui Province 230601, China; Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China; State Key Joint Laboratory of Environmental Simulation and Pollution Control, Research Center for Eco-Environmental Sciences, Chinese Academy of SciencesBeijing 100085, China; NUS Environmental Research Institute, National University of Singapore, 5A Engineering Drive 1, #02-01, Singapore117411, Singapore; Department of Civil and Environmental Engineering, National University of Singapore, 1 Engineering Drive 2, E1A 07-03, Singapore117576, Singapore; China-UK Low Carbon College, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China

Recommended Citation:
Chen Y.,Su J.-Q.,Zhang J.,et al. High-throughput profiling of antibiotic resistance gene dynamic in a drinking water river-reservoir system[J]. Water Research,2019-01-01
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