DOI: 10.1016/j.watres.2018.11.001
Scopus记录号: 2-s2.0-85056218817
论文题名: Aerobic and anaerobic formation and biodegradation of guanyl urea and other transformation products of metformin
作者: Tisler S. ; Zwiener C.
刊名: Water Research
ISSN: 431354
出版年: 2019
起始页码: 130
结束页码: 135
语种: 英语
英文关键词: Antidiabetic
; Biodegradation
; Guanyl urea
; Metformin
; Transformation products
; Waste water treatment
Scopus关键词: Biodegradability
; Biodegradation
; Degradation
; Metabolism
; Urea
; Waste treatment
; Wastewater
; Wastewater treatment
; Water treatment
; Anaerobic conditions
; Anti diabetics
; Biodegradation potentials
; Biodegradation studies
; Dead-end metabolites
; Degradation kinetics
; Metformins
; Transformation products
; Effluents
; 2 amino 4 methylamino 1,3,5 triazine
; 2,4 diamino 1,3,5 triazine
; guanyl urea
; metformin
; methylbiguanide
; unclassified drug
; urea
; activated sludge
; anoxic conditions
; biodegradation
; chemical compound
; concentration (composition)
; degradation
; effluent
; metabolite
; oxic conditions
; reaction kinetics
; sludge
; transformation
; urea
; water treatment
; activated sludge
; anaerobic digestion
; Article
; biodegradability
; biodegradation
; chemical structure
; controlled study
; degradation kinetics
; dry weight
; effluent
; priority journal
; waste water treatment plant
; Bacteria (microorganisms)
英文摘要: The aim of the study was to investigate the biodegradability of guanyl urea (GU) and the behavior of other transformation products (TPs) of Metformin (MF). Most biodegradation studies of MF with activated sludge of waste water treatment plants (WWTPs) showed GU as the only bacterial dead-end metabolite without further degradation. In this study, batch experiments with activated sludge revealed biodegradability of GU. GU degradation was much faster under anaerobic than under aerobic conditions. Degradation kinetics for MF was much slower under anaerobic conditions. Adsorptive removal of up to 20% was an additional elimination process of MF and GU. The batch experiments were conducted with sludge of 2 WWTPs, WWTP 1 showed decreasing concentrations of GU from influent to effluent and the other increasing concentrations. This indicates a different adaption of the sludge to GU and may explain the better GU degradation capability of the sludge from WWTP 1. Furthermore, the biodegradation potential of MF was confirmed and in addition, occurrence of the TPs methylbiguanide (MBG), 2-amino-4-methylamino-1,3,5-triazine (2,4-AMT) and the secondary TP 2,4-diamino-1,3,5-triazine (2,4-DAT) was observed in batch experiments with activated sludge of WWTP 1. After fast formation, degradation in turn was slower, especially for 2,4-AMT. In general, TPs played a minor role in MF and GU degradation. © 2018 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/122174
Appears in Collections: 气候变化事实与影响
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作者单位: Hölderlinstraße 12, 72074 Tübingen, Germany
Recommended Citation:
Tisler S.,Zwiener C.. Aerobic and anaerobic formation and biodegradation of guanyl urea and other transformation products of metformin[J]. Water Research,2019-01-01