globalchange  > 气候变化事实与影响
DOI: 10.1289/ehp.1408095
论文题名:
Natural-Cause Mortality and Long-Term Exposure to Particle Components: An Analysis of 19 European Cohorts within the Multi-Center ESCAPE Project
作者: Rob Beelen; 1 Gerard Hoek; 1 Ole Raaschou-Nielsen; 2 Massimo Stafoggia; 3 Zorana Jovanovic; ersen; 2; 4 Gudrun Weinmayr; 5; 6 Barbara Hoffmann; 6; 7 Kathrin Wolf; 8 Evangelia Samoli; 9 Paul H. Fischer; 10 Mark J. Nieuwenhuijsen; 11; 12 Wei W. Xun; 13; 14 Klea Katsouyanni; 9 Konstantina Dimakopoulou; 9 Aless; ro Marcon; 15 Erkki Vartiainen; 16 Timo Lanki; 17 Tarja Yli-Tuomi; 17 Bente Oftedal; 18 Per E. Schwarze; 18 Per Nafstad; 18; 19 Ulf De Faire; 20 Nancy L. Pedersen; 21 Claes-Göran Östenson; 22 Laura Fratiglioni; 23 Johanna Penell; 20 Michal Korek; 20 Göran Pershagen; 20 Kirsten Thorup Eriksen; 2 Kim Overvad; 24; 25 Mette Sørensen; 2 Marloes Eeftens; 1 Petra H. Peeters; 26; 27 Kees Meliefste; 1 Meng Wang; 1 H. Bas Bueno-de-Mesquita; 10; 27; 28 Dorothea Sugiri; 6; 7 Ursula Krämer; 6; 7 Joachim Heinrich; 29 Kees de Hoogh; 13 Timothy Key; 30 Annette Peters; 8 Regina Hampel; 8 Hans Concin; 31 Gabriele Nagel; 5; 31; rea Jaensch; 5 Alex Ineichen; 32; 33 Ming-Yi Tsai; 32; 33; 34 Emmanuel Schaffner; 32; 33 Nicole M. Probst-Hensch; 32; 33 Christian Schindler; 32; 33 Martina S. Ragettli; 32; 33 Alice Vilier; 35; 36; 37 Françoise Clavel-Chapelon; 35; 36; 37 Christophe Declercq; 38 Fulvio Ricceri; 39 Carlotta Sacerdote; 40 Claudia Galassi; 40 Enrica Migliore; 40; rea Ranzi; 41 Giulia Cesaroni; 3 Chiara Badaloni; 3 Francesco Forastiere; 3 Michail Katsoulis; 42 Antonia Trichopoulou; 42 Menno Keuken; 43 Aleks; ra Jedynska; 43 Ingeborg M. Kooter; 43 Jaakko Kukkonen; 44 Ranjeet S. Sokhi; 45 Paolo Vineis; 13; Bert Brunekreef1; 26
刊名: Environmental Health Perspectives
ISSN: 0091-7210
出版年: 2015
卷: Volume 123, 期:Issue 6
起始页码: 525
语种: 英语
英文摘要: Background: Studies have shown associations between mortality and long-term exposure to particulate matter air pollution. Few cohort studies have estimated the effects of the elemental composition of particulate matter on mortality.

Objectives: Our aim was to study the association between natural-cause mortality and long-term exposure to elemental components of particulate matter.

Methods: Mortality and confounder data from 19 European cohort studies were used. Residential exposure to eight a priori–selected components of particulate matter (PM) was characterized following a strictly standardized protocol. Annual average concentrations of copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc within PM size fractions ≤ 2.5 μm (PM2.5) and ≤ 10 μm (PM10) were estimated using land-use regression models. Cohort-specific statistical analyses of the associations between mortality and air pollution were conducted using Cox proportional hazards models using a common protocol followed by meta-analysis.

Results: The total study population consisted of 291,816 participants, of whom 25,466 died from a natural cause during follow-up (average time of follow-up, 14.3 years). Hazard ratios were positive for almost all elements and statistically significant for PM2.5 sulfur (1.14; 95% CI: 1.06, 1.23 per 200 ng/m3). In a two-pollutant model, the association with PM2.5 sulfur was robust to adjustment for PM2.5 mass, whereas the association with PM2.5 mass was reduced.

Conclusions: Long-term exposure to PM2.5 sulfur was associated with natural-cause mortality. This association was robust to adjustment for other pollutants and PM2.5.
URL: https://ehp.niehs.nih.gov/1408095
Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/12541
Appears in Collections:气候变化事实与影响
气候变化与战略

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
ehp.1408095.alt.pdf（1279KB）期刊论文作者接受稿开放获取
CC BY-NC-SA
View Download

作者单位: 1Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands; 2Danish Cancer Society Research Center, Copenhagen, Denmark; 3Department of Epidemiology, Lazio Regional Health Service, Rome, Italy; 4Center for Epidemiology and Screening, Department of Public Health, University of Copenhagen, Copenhagen, Denmark; 5Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany; 6IUF–Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany, and; 7Medical Faculty, University of Düsseldorf, Germany; 8Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; 9Department of Hygiene, Epidemiology and Medical Statistics, Medical School, University of Athens, Athens, Greece; 10National Institute for Public Health and the Environment, Bilthoven, the Netherlands; 11Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; 12Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública-CIBERESP), Madrid, Spain; 13MRC-HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; 14University College London, CeLSIUS, London, United Kingdom; 15Unit of Epidemiology and Medical Statistics, Department of Public Health and Community Medicine, University of Verona, Verona, Italy; 16Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland; 17Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland; 18Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway; 19Institute of Health and Society, University of Oslo, Oslo, Norway; 20Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; 21Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 22Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; 23Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden; 24Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark; 25Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark; 26Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; 27Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College, London, United Kingdom; 28Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, the Netherlands; 29Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center of Environmental Health, Neuherberg, Germany; 30Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; 31Agency for Preventive and Social Medicine, Bregenz, Austria; 32Swiss Tropical and Public Health Institute, Basel, Switzerland; 33University of Basel, Basel, Switzerland; 34Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA; 35Inserm, Centre for research in Epidemiology and Population Health (CESP), Nutrition, Hormones and Women’s Health team, Villejuif, France; 36University Paris Sud, Villejuif, France; 37IGR, Villejuif, France; 38French Institute for Public Health Surveillance (InVS), Saint-Maurice, France; 39Human Genetics Foundation-HuGeF, Turin, Italy; 40Unit of Cancer Epidemiology, AO Citta’ della Salute e della Scienza-University of Turin and Center for Cancer Prevention, Turin, Italy; 41Environmental Health Reference Centre-Regional Agency for Environmental Prevention of Emilia-Romagna, Modena, Italy; 42Hellenic Health Foundation, Athens, Greece; 43TNO, Netherlands Organisation for Applied Scientific Research, Utrecht, the Netherlands; 44Finnish Meteorological Institute, Helsinki, Finland; 45Centre for Atmospheric and Instrumentation Research (CAIR), University of Hertfordshire, Hatfield, Hertfordshire, United Kingdom

Recommended Citation:
Rob Beelen,1 Gerard Hoek,1 Ole Raaschou-Nielsen,et al. Natural-Cause Mortality and Long-Term Exposure to Particle Components: An Analysis of 19 European Cohorts within the Multi-Center ESCAPE Project[J]. Environmental Health Perspectives,2015-01-01,Volume 123(Issue 6):525
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Rob Beelen]'s Articles
[1 Gerard Hoek]'s Articles
[1 Ole Raaschou-Nielsen]'s Articles
百度学术
Similar articles in Baidu Scholar
[Rob Beelen]'s Articles
[1 Gerard Hoek]'s Articles
[1 Ole Raaschou-Nielsen]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Rob Beelen]‘s Articles
[1 Gerard Hoek]‘s Articles
[1 Ole Raaschou-Nielsen]‘s Articles
Related Copyright Policies
Null
收藏/分享
文件名： ehp.1408095.alt.pdf
格式： Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.