Global Diversity of the Brachypodium Species Complex as a Resource for Genome-Wide Association Studies Demonstrated for Agronomic Traits in Response to Climate
GREATER EARLY VIGOR
; MODEL GRASS
; FLOWERING-TIME
; TRANSPIRATION EFFICIENCY
; GENETIC ARCHITECTURE
; DARK RESPIRATION
; MATURE LEAVES
; WHEAT
; POPULATION
; DISTACHYON
WOS学科分类:
Genetics & Heredity
WOS研究方向:
Genetics & Heredity
英文摘要:
The development of model systems requires a detailed assessment of standing genetic variation across natural populations. The Brachypodium species complex has been promoted as a plant model for grass genomics with translation to small grain and biomass crops. To capture the genetic diversity within this species complex, thousands of Brachypodium accessions from around the globe were collected and genotyped by sequencing. Overall, 1897 samples were classified into two diploid or allopolyploid species, and then further grouped into distinct inbred genotypes. A core set of diverse B. distachyon diploid lines was selected for whole genome sequencing and high resolution phenotyping. Genome-wide association studies across simulated seasonal environments was used to identify candidate genes and pathways tied to key life history and agronomic traits under current and future climatic conditions. A total of 8, 22, and 47 QTL were identified for flowering time, early vigor, and energy traits, respectively. The results highlight the genomic structure of the Brachypodium species complex, and the diploid lines provided a resource that allows complex trait dissection within this grass model species.
1.Australian Natl Univ, ARC Ctr Excellence Plant Energy Biol, Canberra, ACT 200, Australia 2.Australian Natl Univ, Ecogen & Bioinformat Lab, Res Sch Biol, Canberra, ACT 200, Australia 3.Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA 4.ARS, Soil & Water Management, USDA, St Paul, MN 55108 USA 5.Joint Genome Inst, Dept Energy, Walnut Creek, CA 94598 USA 6.Grains Res & Dev Corp, Canberra, ACT, Australia 7.Oak Ridge Natl Lab, Oak Ridge, TN 37830 USA
Recommended Citation:
Wilson, Pip B.,Streich, Jared C.,Murray, Kevin D.,et al. Global Diversity of the Brachypodium Species Complex as a Resource for Genome-Wide Association Studies Demonstrated for Agronomic Traits in Response to Climate[J]. GENETICS,2019-01-01,211(1):317-331