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The Tibetan Plateau (TP) has important influences on regional and global climate change. Here, we perform an in-depth study of the relationship between cloud parameters and meteorological factors over the TP. The spatiotemporal variations in cloud cover and cloud optical thickness over the TP during the daytime from 2003 to 2015 are analysed using the Aqua-MODIS level 2 atmospheric product data MYD06. Results show that the annual average cloud cover over the TP decreases from the southeast to the northwest. The cloud cover of the western TP is highest in spring and lowest in autumn, while the cloud cover of the eastern TP is higher in spring and summer. The cloud covers in most areas of the TP exceed 30% in spring and summer, and the cloud optical thickness in the southeastern TP exceeds 10 in summer, with substantial cloud cover and cloud optical thickness changes. Compared to other seasons, the cooling effect of the near surface cloud net radiative forcing is greater during daytime in summer, which is likely associated with thick cloud optical thickness or large cloud cover. The results of the analysis of relationships among cloud cover, water vapour and air temperature show that positive correlations exist between cloud cover and water vapour, and that significantly negative correlations exist between cloud cover and air temperature over the TP. Combined with the analysis of variation features in the cloud parameters and meteorological factors, we find that water vapour variations during the daytime over the TP lead to cloud cover changes, which affect the air temperature variations over the TP by the cooling effects of clouds, especially in summer.