gchange  > 气候变化事实与影响
DOI: 10.1289/ehp.1306940
Title:
Influence of Urbanicity and County Characteristics on the Association between Ozone and Asthma Emergency Department Visits in North Carolina
Author: Jason D. Sacks; 1 Ana G. Rappold; 2 J. Allen Davis Jr.; 1 David B. Richardson; 3 Anna E. Waller; 4; Thomas J. Luben1
Source Publication: Environmental Health Perspectives
ISSN: 0091-7435
Indexed By: SCI-E
Publishing Year: 2014
Volume: Volume 122, Issue:Issue 5
pages begin: 506
Language: 英语
Subject in Chinese: 颗粒物质 ; 空气质量 ; 颗粒物
Subject: PARTICULATE MATTER ; AIR QUALITY
English Abstract: Background: Air pollution epidemiologic studies, often conducted in large metropolitan areas because of proximity to regulatory monitors, are limited in their ability to examine potential associations between air pollution exposures and health effects in rural locations.

Methods: Using a time-stratified case-crossover framework, we examined associations between asthma emergency department (ED) visits in North Carolina (2006–2008), collected by a surveillance system, and short-term ozone (O3) exposures using predicted concentrations from the Community Multiscale Air Quality (CMAQ) model. We estimated associations by county groupings based on four urbanicity classifications (representative of county size and urban proximity) and county health.

Results: O3 was associated with asthma ED visits in all-year and warm season (April–October) analyses [odds ratio (OR) = 1.019; 95% CI: 0.998, 1.040; OR = 1.020; 95% CI: 0.997, 1.044, respectively, for a 20-ppb increase in lag 0–2 days O3]. The association was strongest in Less Urbanized counties, with no evidence of a positive association in Rural counties. Associations were similar when adjusted for fine particulate matter in copollutant models. Associations were stronger for children (5–17 years of age) compared with other age groups, and for individuals living in counties identified with poorer health status compared with counties that had the highest health rankings, although estimated associations for these subgroups had larger uncertainty.

Conclusions: Associations between short-term O3 exposures and asthma ED visits differed by overall county health and urbanicity, with stronger associations in Less Urbanized counties, and no positive association in Rural counties. Results also suggest that children are at increased risk of O3-related respiratory effects.
Related Link: https://ehp.niehs.nih.gov/1306940
Citation statistics:
被引频次[WOS]:32   [查看WOS记录]     [查看WOS中相关记录]
Document Type: 期刊论文
Identifier: http://119.78.100.177/globalchange/handle/2HF3EXSE/12764
Appears in Collections:气候变化事实与影响
气候变化与战略

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Affiliation: 1National Center for Environmental Assessment, Office of Research and Development, and 2National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA; 3Department of Epidemiology, and 4Department of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Recommended Citation:
Jason D. Sacks,1 Ana G. Rappold,2 J. Allen Davis Jr.,et al. Influence of Urbanicity and County Characteristics on the Association between Ozone and Asthma Emergency Department Visits in North Carolina[J]. Environmental Health Perspectives,2014-01-01,Volume 122(Issue 5):506
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