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From 1992 to 2015, ecological environment has been threatened by the changes of cropland around the world. In order to evaluate the impact of cropland changes on ecosystem, we calculated the response of terrestrial ecosystem service values (TESVs) variation to cropland conversion based on land-use data from European Space Agency (ESA). The results showed that cropland changes were responsible for an absolute loss of $166.82 billion, equivalent to 1.17% of global TESVs in 1992. Among the different regions, the impact of cropland changes on TESVs was significant in South America and Africa but not obvious in Oceania, Asia and Europe. Cropland expansion from tropical forest was the main reason for decreases in TESVs globally, especially in South America, Africa and Asia. The effect of wetland converted to cropland was notable in North America and Europe while grassland converted to cropland played an important role in Oceania, Africa and Asia. In Europe, the force of urban expansion cannot be ignored as well. The conversion of cropland to tropical or temperate forest partly compensated for the loss of TESVs globally, especially in Asia.