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Heat stress has severe effects in organisms. Dairy cattle is susceptible to suffer behavioral, physiological and reproductive damages due heat stress. Breeding searching for tolerant heat stress genes and their incorporation in crossbreeding programs has gained interest in dairy cattlemen concerned by the global warming and greenhouse effect in the environment. This review shows and update of the crossbreeding in dairy cattle in both hemispheres. Here, is reviewed the effect of heat stress on dairy cattle; the mechanism of autoregulation; the benefits of the heterosis in crossbreeding cattle by hybridization; the body condition score in crossbred dairy cattle; the yields in crossbreds; here is also discussed that even when there have been many crossbreeding in dairy cattle, but when the producer choose a system crossbreeding in dairy cows always mostly contemplate only body weight, body condition score, dry matter intake, and feed efficiency. Is suggested to contemplate other traits like genetic potential, lactation (305 d), lactation number, fertility rate, and economic impact to observe clarity the potential of each crossbred in dairy cattle in the future.