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The water climate-food security nexus is uniquely vulnerable in Central Asia, a region replete with transboundary water conflicts, shortages in land and water resources and high sensitivity to climate change. Using a water balance for the Amu Darya River Basin, we present a synthetic evaluation of future water use, crop yields, land and water productivities for the period 2016 to 2055 in Ahal, Dashoguz, Lebap, and Mary provinces in Turkmenistan. Modeled fut socio-economic scenarios include food security and diet change (FSD), export-oriented sustainable adaptation (ESA) and business as usual (BAU). Results show that water requirements and water deficits during growing seasons will exhibit a decreasing trend from 2016 to 2055 in most provinces under all three scenarios. Crop yields and land and water productivities will likely increase in the four provinces under both the FSD and ESA scenarios. Mary province had the highest mean income and losses of irrigated agriculture, with an annual average value of about 7 x 10(8) USD/year and 1.5 x 10(3) USD/year, respectively. Ahral province showed the largest annual mean land and irrigation water productivities for all three scenarios, up to about 800 USD/ha/year and 0.40 USD/m(3)/year respectively. Results obtained from this study provide tools to assist resource managers to identify vulnerabilities in the nexus of water, land and climate to ensure food security, water management, and sustainable development. (C) 2019 Elsevier Ltd. All rights reserved.