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Climate engineering arises as one of the potential methods that could contribute to meeting the 1.5 degrees C global warming target agreed under the Paris Agreement. We examine how permafrost and high-latitude vegetation respond to the large-scale implementation of climate engineering. Specifically, we explore the impacts of applying the solar radiation management method of stratospheric aerosol injections (SAI) on permafrost temperature and the global extent of near-surface permafrost area. We compare the RCP8.5 and RCP4.5 scenarios to several SAI deployment scenarios using the Norwegian Earth System Model (CE1 = moderate SAI scenario to bring down the global mean warming in RCP8.5 to the RCP4.5 level, CE2 = aggresive SAI scenario to maintain the global mean temperature toward the preindustrial level). We show that large-scale application of SAI may help slow down the current rate of permafrost degradation for a wide range of emission scenarios. Between the RCP4.5 and CE1 simulations, the differences in the permafrost degradation may be attributed to the spatial variations in surface air temperature, rainfall, and snowfall, which lead to the differences in the timing of permafrost degradation up to 40 years. Although atmospheric temperatures in CE1 and RCP4.5 simulations are similar, net primary production is higher in CE1 due to CO2 fertilization. Our investigation of permafrost extent under large-scale SAI application scenarios suggests that circum-Arctic permafrost area and extent is rather sensitive to temperature changes created under such SAI application. Our results highlight the importance of investigating the regional effects of climate engineering, particularly in high-latitude ecosystems.