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Monitoring and mapping the sensitivity of grassland ecosystems to climate change is crucial for developing sustainable local grassland management strategies. The sensitivity of alpine grasslands to climate change is considered to be high on the Qinghai-Tibet Plateau (QTP), yet little is known about its spatial pattern, and particularly the variations between different elevations. Here, based on the Normalized Difference Vegetation Index (NDVI) and three climate variables (air temperature, precipitation, and solar radiation), we modified a vegetation sensitivity index-approach to capture the relative sensitivity of alpine grassland productivity to climate variability on the QTP during 2000-2016. The results show that alpine grasslands on the southern QTP are more sensitive to climate variability overall, and that the climate factors driving alpine grassland dynamics are spatially heterogeneous. Alpine grasslands on the southern QTP are more sensitive to temperature variability, those on the northeastern QTP display strong responses to precipitation variability, and those on the central QTP are primarily influenced by a combination of radiation and temperature variability. The sensitivity of alpine grasslands to climate variability increases significantly along an elevational gradient, especially to temperature variability. This study underscores that alpine grasslands at higher elevations on the QTP are more sensitive to climate variability than those at lower elevations at the regional scale. (C) 2019 Elsevier B.V. All rights reserved.