This article clarifies the mechanism of how LUCC affects the regional climate focusing on biogeophysical processes, and impacts of LUCC such as deforestation/afforestation, urbanization, agricultural activities on regional climate changes were summarized. Climate model is important to study regional climate effects by LUCC. Remote sensing is known to give more detailed description to land parameters in such models,contributing to improvements in the simulation results. Existing issues in such studies are discussed. In the future, uncertainty in simulation should be reduced. Knowledge of landscape ecology can be used to better understand relationship between human activities and climate changes,and to optimize plans for regional land use to adapt to climate changes.