Siberia is an important sensitive area with regard to global environmental change. Due to the limited availability of high resolution remote sensing data, previously there was a general lack of in-depth understanding of land cover and change in Siberia. Based on the land cover classification of China's 30 m global land cover(GLC) data product (GlobeLand30) in 2000 and 2010, this study analyzed the progress of land cover change in Siberia between 2000 and 2010 using spatial statistical method and land cover type transition matrix. Land cover changes in Siberia showed significant spatial and temporal variations between 2000 and 2010. Overall, the area that experienced most clear land cover change was west Siberia. The area of forests and grasslands decreased substantially and the change mainly took place in the traditional forest industry regions. The total area of wetland significantly increased and this change occurred mainly in the River Ob and Yenisei in west Siberia. Cultivated land decreased slightly mainly in the traditional agricultural region of the southwest. Built-up areas expanded rapidly, which mainly distributed in cities along the Trans-Siberian Railway. Land cover change in Siberia showed distinct temporal and spatial disparities primarily due to two reasons: industrial development and climate warming..