Many researches have shown that most glaciers in the world experiencing a general reduction in area due to climate warming in recent decades. Monitoring the glacier change by multiple remote sensing images provides a useful data set. Based on Landsat TM /ETM + /OLI images,glacier boundaries were extracted with ratio threshold and visual interpretation method,and the characteristics of glacier variation were also analyzed in the Nubra basin,Karakoram Mountains,during 1993-2015. The results show that,compared with other regions in the Tibetan Plateau,the glacier retreat was smaller in the study area. The total glacierized area in the study area had shrunk by 103.24 km~2,accounting for 4.64% of the total glacierized area,at a rate of 0.20%·a~(-1) as a whole. It can be concluded that the increase of air temperature is the main factor leading to the shrinkage of glacierized area in the study area. The retreat range of glaciers smaller than or equal to 0.1 km~2 was the largest,and that of larger glaciers shrank at a relatively small rate. Glaciers with different aspects shrank differently. The maximum shrinkage occurred in northward glaciers,because they were small-scale,more sensitive to climate change. The eastward glaciers had the minimum shrinkage. There were nine glaciers had clearly advanced during 1993-2015.