Northwest arid area of China is of the ecological fragile areas,so it has great importance to study the spatial variability of major climatic resources for making full use of climate resources,coordinating regional ecological environment and socio - economic development. In this study,based on seven major meteorological factors of the 191 meteorological stations in the northwest arid area,classical statistics and geostatistical analysis methods were used to study the spatial variability and distribution of meteorological factors. Results showed that: (1) The coefficient of variation of dryness > 1,and the coefficient of variation of the rest of factor was between 0.157 and 0.712,indicated that various meteorological factors presented medium or strong spatial variation characteristic. (2) The basic effect value of each factor was greater than 0.75,indicating that meteorological factors were mainly influenced by structural factors (natural factors),and would not easily change or be difficult to change in the short term. (3) Precipitation and relative humidity showed an increasing trend from northwest to southeast; evaporation and dryness performed the opposite characteristics. Average annual temperature peak appeared in southern Xinjiang and ShanXi. Sunshine duration and wind speed had a descending trend overall from North to South. The proposed research method in this research for studying the spatial variability of meteorological factors was scientifically credible; furthermore,the method has a certain theoretical reference value for climate resources spatial variation of the same type region. It's helpful to grasp the characteristics of climate change and provides scientific basis for husbandry by studying the spatial variation features of climate change in northwest arid area.