Based on analyzed the major elements contents and other geochemical parameters of the red weathering crust from the Shicao profile in the southern of Liaoning Province, the geochemical characteristics of the weathering process and paleoclimate evolution were discussed. The results showed that the major elements are mainly composed of SiO_2, Al_2O_3 and Fe_2O_3. Compared to the bedrock, Ca has been leached out strongly, while other major elements relatively enriched in the red weathering crust of Shicao profile. In general, the intensity of chemical weathering in Shicao profile was lower than the red weathering crust from the southern China, which indicated a moderate chemical weathering intensity under warm and moist climate conditions. There are four stages of weathering process in the Shicao profile that can be assigned as intensely weathering, weakening weathering, intensifying weathering, and relatively weaker weathering. Since the chemical weathering intensity of the red crust is sensitive to climate change, the geochemical parameters can be used to reconstruct the paleoclimate environment. The paleoclimate of the southern of Liaoning Province, which in the weathering period of the Shicao profile, has undergone four stages. That is hot and humid, warm and wet, return warming, relatively warm and wet.