Effects of water changes and nitrogen deposition on the carbon cycle in alpine wetlands are the focus in the global change ecology. The primary objective of this study was to investigate the dynamics of soil CO_2 emission in alpine wetland under the conditions of alternating dry-wet(soil water changing)and simulated nitrogen deposition(nitrogen addition).Water changing treatments were 100%, 70%, 50%, 40% and 25% of water filling soil porosity(WFPS), and nitrogen addition treatments were 0 kg·hm~(-2)·a~(-1)(N0), 10 kg·hm~(-2)·a~(-1)(N10)and 100 kg·hm~(-2)·a~(-1)(N100). Changes of soil CO_2 emissions under these treatments were measured in alpine wetland soils of Bayinbuluk using the indoor control experiments. Results showed that:The soil CO_2 emission rates and cumulative emission increased with the increase of WFPS and nitrogen addition. In the soil process from wet to dry, soil CO_2 emission rate decreased with the reduction of soil moisture content. The cumulative CO_2 emission in the first process from wet to dry was significantly higher than the rest soil water changing process. The contents of soil total nitrogen(TN), NO_3~- -N, NH_4~+ -N and soil organic carbon(SOC)increased with the increase of soil moisture content and nitrogen addition, while soil organic nitrogen(SON)reduced in the similar treatment changes of soil water treatments and nitrogen addition treatments. Significantly positive correlations between soil moisture content and the soil CO_2 emission rates and between nitrogen addition and the soil CO_2 emission rates were found in this study. The soil CO_2 emission rate was significantly negative correlated with SON and SOC, while it was significantly positive correlated with TN, NO_3~--N and NH_4~+-N. These results provide a scientific basis for the further understanding of the changes of soil CO_2 emission under the conditions of nitrogen deposition and extreme climate change in arid alpine wetlands.