globalchange  > 气候变化事实与影响
CSCD记录号: CSCD:6208074
论文题名:
酿酒酵母木糖转运基因研究进展
其他题名: Research Progress on Xylose Transporters of Saccharomyces cerevisiae
作者: 黄俊1; 吴仁智1; 陆琦1; 芦志龙1
刊名: 中国生物工程杂志
ISSN: 1671-8135
出版年: 2018
卷: 38, 期:2, 页码:773-779
语种: 中文
中文关键词: 木糖 ; 转运基因 ; 酿酒酵母
英文关键词: Xylose ; Transporter gene ; Saccharomyces cerevisiae
WOS学科分类: BIOTECHNOLOGY APPLIED MICROBIOLOGY
WOS研究方向: Biotechnology & Applied Microbiology
中文摘要: 由于对全球变暖等日益严重的环境问题的担忧,生产生物乙醇等清洁能源的技术正受到世界各国越来越多的关注。较之以粮食为原料生产乙醇,木质纤维素生产生物乙醇具有更大的发展潜力,因其来源广泛,廉价且可再生。以木质纤维素生产生物乙醇已经取得长足进步,但仍面临几个主要问题,比如天然酿酒酵母不能利用木糖发酵乙醇,木质纤维素酶成本过高,木质纤维素预处理环节成本高等。已经有基因改造的酵母菌株可以利用戊糖和己糖进行生物乙醇生产。然而,这些菌株对木糖的利用效率很低。这主要是因为酿酒酵母缺乏高效的特异性木糖转运基因,木糖运输依赖已糖转运基因。为了提高木糖利用速度,已有不少方法成功应用于构建重组酵母细胞。现对酵母木糖转运基因的最新研究进展进行简要概述。
英文摘要: Technologies for the production of biothanol are receiving increased attention around the world owing to concerns over the global warming.Lignocellulosic biomass is a great potential resource for the production of biofuels because it is largely abundant,inexpensive and renewable organic material.Significant efforts,many of which have been successful,have been made to convert these lignocellulosic biomass to valuable products,such as biofuels.Sustainable development in lignocellulosic bioethanol production has major challenge due to high cost of production.There are several issues such as efficient utilization of pentose sugars present in lignocelluloses,economical production of lignocellulolytic enzymes with high specificity,cost-effective pre-treatment of lignocellulosic biomass,etc.Genetically modified yeast strains have been approached to utilize pentose and hexose sugars for bioethanol production.However,these strains showed limited xylose consumption.Saccharomyces cerevisiae rely on the capacity of endogenous hexose transporters for xylose uptake,since S.cerevisiae lacks a xylose-specific transport system.Hence,there are several strategies that have been applied to engineer the yeasts which could improve the xylose transportation.latest advancements in S.cerevisiae xylose transporter genes were discussed.
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/155389
Appears in Collections:气候变化事实与影响

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作者单位: 1.广西科学院
2.广西科学院, 国家非粮生物质能源研究工程中心
3.生物质能源酶解技术国家重点实验室, 南宁
4.南宁,
5.530007
6.530007

Recommended Citation:
黄俊,吴仁智,陆琦,等. 酿酒酵母木糖转运基因研究进展[J]. 中国生物工程杂志,2018-01-01,38(2):773-779
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