Based on literature review, we clarified the concept of Eco-geography after thorough discussion and discrimination from related disciplines such as Biogeography, Eco-geographical Planning and Macroecology. We considered that Eco-geography is the interdisciplinary science between Ecology and Geography. It concerns the geospatial pattern and/or temporal change of biotic interactions and ecological processes of ecosystems and how they are coupled with geographical parameters. The aim of Eco-geography is to demonstrate the universal rules and underlying mechanisms of biotic interactions and ecological processes of ecosystems along various environmental gradients and/or at different time scale. Meanwhile, we discussed several classical ecographical studies, particularly those from field controlled experiments in global change and other areas: 1) Global litter decomposition and carbon sink at different climatic regions; 2) Carbon flux and carbon sink of major terrestrial ecosystems in China; 3) Fragility and adaptability of terrestrial ecosystems along NECT and NSTEC transects of China; 4) Ecosystem studies of temperate grassland transect in northern China. Our aim is to facilitate the development of Eco-geography by clarifying the concept and highlighting the future directions. Fur future eco-graphical study, we need to pay special attention to the following aspects: 1) To strengthen the geospatial network study on ecological processes based on field stations and facilities affiliated with National Ecosystem Research Network (NERN) of China; 2) To launch key project in support of innovative ideas with well-designed field controlled experiments along geospatial gradient; 3) To enhance the large scale application of remote sensing technology coupled with long-term monitoring of ecological processes.