In this paper, the average daily temperature data from 41 meteorological stations in Chinese oases where the Populus euphratica trees grow during the period from 1960 to 2016 were used to analyze the spatiotemporal response of the leaf-yellow period of P. euphratica to climate change and its regional difference. In the study the methods of multi-year trend line, inverse distance weighted interpolation (IDW) ,Morlet wavelet power spectrum, Mann-Kendall mutation test and correlation analysis were applied. The results revealed that the beginning and ending dates of the leaf yellow of P. euphratica were postponed over the last 57 years,and the leaf-yellow period was gradually prolonged. The change trend rates were 0. 72,1 . 39(alpha≥0. 05) and 0. 66 days /decade respectively,which revealed that the beginning and ending dates of the leaf yellow of P. euphratica became earlier along a southwestnortheast transect of Chinese oases. Especially the postponement trend was the most obvious in the Qaidam Oasis but not in the oases in south Xinjiang. In addition to north Xinjiang, the leaf-yellow period became shorter along a southnorth transect of Chinese oases,and the spatial disparity was extremely significant. There were the 2. 2 -,3 . 0 - and 5. 2 - 5. 6 - year short cycles of the beginning and ending dates of leaf yellow of P. euphratica,and they were consistent with the 2 - 4 - year general atmospheric circulation and the 2 - 7 - year El Nino events. Mutations of the starting and ending dates and periods of leaf yellow of P. euphratica occurred in 2003,1 990 and 1961 respectively, but they were different from different oases. There were the significant correlations among the starting and ending dates and period of leaf yellow of P. euphratica and the mean monthly temperatures in the periods from June to August, from July to September and from September to November,and their correlation coefficients were 0. 703,0 . 697, and 0. 715 (alpha≥0. 001) , respectively. The results showed that the response of the leaf-yellow period of P. euphratica to global warming was sensitive and regionally different.