The mathematical statistics, trend rate method,Mann-Kendall mutation test and wavelet analysis were used to study the characteristics, trends and spatial difference of climate change in North Xinjiang in the past 56 years based on the daily temperature and precipitation data from 40 stations in North Xinjiang from 1961 to 2016. The results showed that, during the study period, there was generally a warming-wetting climate change trend. The annual average temperature increased by 0. 34 ℃·(10a) ~(- 1), and the increase rate of annual precipitation was 12. 05 mm· (10a) ~(- 1) . Mann-Kendall mutation test showed that the temperature increased after 1991,and the precipitation increased gradually after its mutation in 1987; there were the 6 -, 14 - and 28 - year periodical changes of annual mean temperature, and the 4 -, 12 - and 22 - year ones of annual precipitation. In terms of spatial differences, the temperature increase was higher in the east and west than that in the north and south, and the precipitation increase was higher in the mountainous regions than that in the plains and basins and higher in the west than that in the east.