Based on the monthly maximum and minimum temperature data at Wuhan meteorological station in 1906-2015, annual mean temperature during the 110 years was reconstructed and the temporal change was analyzed. The main conclusions are: (1) Annual mean temperature of Wuhan showed multi-decadal variations. Two warm periods were experienced during 1906-1946 and 1994-2015; and between 1947 and 1993, annual mean temperature was relatively low. (2) At multi-decadal temporal scales, annual mean temperature of Wuhan showed several significant warming and cooling trends. The largest warming trends at 30-and 50-year scales were detected during 1980-2009 and 1960-2009, with linear trends amounting to 2.670.48 ℃/30a and 2.20 0.50 ℃/50a, respectively. The strongest cooling trends for the same temporal scales were detected for 1928-1957 and 1925-1974, with linear trends being-1.230.48 ℃/30a and-1.400.35 ℃/50a, respectively. (3) During the 110 years, there existed three abrupt changes in Wuhan annual mean temperature. During the early 1920s and the mid-late 1990s, temperature of Wuhan turned from cold to warm conditions. In the 1940s, the change was to the opposite. (4) Comparing temperature change of Wuhan with global, hemispheric, and China's country scales, the temperatures showed similar temporal evolution, with Wuhan exhibiting greater amplitude of change. The recent pause in global warming was also observed inWuhan.