globalchange  > 气候变化与战略
DOI: 10.1016/j.sajb.2020.01.045
论文题名:
Morinda morindoides: A systematic review of its therapeutic activities
作者: Mohammed A.; Tam D.N.H.; Vu T.L.H.; Tieu T.M.; Elfaituri M.K.; Trinh N.N.; Sagheir E.A.; Tran L.; Loc T.T.H.; Low S.K.; Mizukami S.; Hirayama K.; Huy N.T.
刊名: South African Journal of Botany
ISSN: 2546299
出版年: 2020
卷: 131
语种: 英语
英文关键词: Bioactivity ; Morinda morindoides ; Pharmacological ; Systematic review
Scopus关键词: bioactivity ; blood ; drug ; literature review ; medicinal plant ; metabolism ; safety ; taxonomy ; Africa ; Europe ; New York [United States] ; United States ; Animalia ; Bacteria (microorganisms) ; Morinda morindoides ; Scopus
英文摘要: Background: Morinda morindoides has been used as herbal medicine in Africa for a long time. It possesses potential therapeutic activities such as antiplasmodial, antispermatogenic, anti-bacterial, anti-fungal, anti-diarrheal effects, stomach pain and constipation reliefs. However, there has been no literature summarising its potential effects. This study therefore aims to systematically review the therapeutic activities of this medicinal plant as well as its pharmacological activities. Materials and methods: Nine databases were selected to search suitable articles namely MEDLINE (PubMed), ISI, Scopus, Google Scholar, Global Health Library (GHL), Virtual Health Library (VHL), POPLINE, New York Academy of Medicine gray Literature Report (NYAM), and System for Information on gray Literature in Europe (SIGLE). Based on inclusion and exclusion criteria, we included 54 papers for the systemic review. Results: Briefly, in vitro studies showed that M. morindoides possessed anti-malarial, anti-bacterial, anti-fungal, anti-amoebic, anti-larval, spasmolytic, anti-oxidant effects and complementary modulation. Moreover, those effects were emphasized in animal studies. The plant also showed positive activities on body metabolism studied on animal models such as hypotensive, hypoglycemic, hypolipidemic actions. M. morindoides showed its safety on animals’ organs as it did not dramatically change in blood parameters or injure cardiac tissues. However, there were many inconsistent results from various studies in terms of its benefits while its extracts showed a wide range of safety on different cells. Conclusion: M. morindoides has proven to have potential therapeutic effects in vitro and in vivo models. Therefore, higher quality studies on human are necessary to be conducted, which can provide stronger evidence to confirm M. morindoides's effects. © 2020 SAAB
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/158075
Appears in Collections:气候变化与战略

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作者单位: Faculty of medicine, Al-Azhar University, Cairo, 11651, Egypt; Online Research Club (http://onlineresearchclub.org), Nagasaki, 852-8523, Japan; Asia Shine Trading & Service Co., LTD., Ho Chi Minh City, 70000, Viet Nam; Department of Bioengineering, University of California, Berkeley, CA 94720-1234, United States; Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada; Faculty of Medicine, University of Tripoli, Tripoli, 13555, Libyan Arab Jamahiriya; Faculty of Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada; Faculty of Medicine, Zawia University16418, Libyan Arab Jamahiriya; Institute of Research and Development, Duy Tan University, Da Nang, 550000, Viet Nam; School of Medicine, Viet Nam National University Ho Chi Minh City70000, Viet Nam; School of Medicine, Faculty of Health and Medical Sciences, Taylor's University, Selangor, 47500, Malaysia; Department of Immunogenetics, Department of Immune Regulation, Institute of Tropical Medicine (NEKKEN), Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, 852-8523, Japan; Evidence Based Medicine Research Group & Faculty of Applied Sciences, Ton Duc Thang University, 19 Nguyen Huu Tho, Ho Chi Minh City, 70000, Viet Nam; Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, 70000, Viet Nam

Recommended Citation:
Mohammed A.,Tam D.N.H.,Vu T.L.H.,et al. Morinda morindoides: A systematic review of its therapeutic activities[J]. South African Journal of Botany,2020-01-01,131
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