globalchange  > 气候变化与战略
DOI: 10.1016/j.envres.2020.109183
论文题名:
Temporal trends in the mortality rate of Alzheimer's disease and other dementias attributable to smoking, 1990–2017
作者: Jiang Y.; Man Q.; Liu Z.; Wang Y.; Suo C.; Jin L.; Dong Q.; Cui M.; Chen X.
刊名: Environmental Research
ISSN: 139351
出版年: 2020
卷: 184
语种: 英语
英文关键词: Alzheimer's disease ; Dementia ; Disease burden ; Mortality ; Smoking
Scopus关键词: disease ; geographical region ; mortality ; nervous system disorder ; smoking ; spatiotemporal analysis ; temporal variation ; adult ; aged ; Alzheimer disease ; Article ; Asia ; attributable risk ; controlled study ; dementia ; female ; geography ; global disease burden ; groups by age ; human ; major clinical study ; male ; middle aged ; mortality rate ; multicenter study ; population growth ; prevalence ; priority journal ; risk factor ; risk reduction ; sex difference ; smoking ; standardized mortality ratio ; temporal analysis ; tobacco ; trend study ; very elderly ; Nicotiana tabacum
英文摘要: Background: Smoking is a well-defined modifiable risk factor for dementia. Understanding national temporal trends of dementia deaths due to smoking is critical for prioritizing action for the global prevention of dementia, as well as smoking prevention. We aimed to estimate the patterns and temporal trends of smoking-attributable dementia-related deaths for 195 countries from 1990 to 2017. Methods: Detailed data on dementia deaths attributable to smoking were obtained from the Global Burden of Disease Study 2017. The estimated annual percentage change (EAPC) was used to quantify the temporal trends in the age-standardized mortality rate (ASMR) of dementia attributable to smoking by age, sex, region, and country. Results: In 2017, approximately 2.51 million deaths attributable to dementia occurred globally; among them, 317,747 dementia-related deaths were attributable to smoking. The corresponding ASMR decreased by 31.1% from 6.33 per 100,000 population in 1990 to 4.36 per 100,000 population in 2017, with an EAPC of −1.43 (95% CI -1.48, −1.37). The reduction in the ASMR in women (EAPC = −2.13; 95% CI -2.18, −2.08) was more pronounced than that in men (EAPC = −1.26; 95% CI -1.32, −1.20). Most geographic region have achieved significant declines in ASMRs since 1990; however, Central Asia and 24 countries and territories showed increased trends in ASMRs over the same period. Conclusions: Despite large reductions in the ASMRs of dementia attributable to smoking over the past three decades, the corresponding number of deaths has steadily increased due to population growth and aging. The ASMR trend patterns were heterogeneous across countries, and there were undesirable increases in the dementia ASMR in some countries. Strengthened efforts for tobacco prevention are still needed to reduce the disease burden due to smoking, particularly in countries where the dementia ASMR is increasing. © 2020 Elsevier Inc.
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/158294
Appears in Collections:气候变化与战略

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作者单位: State Key Laboratory of Genetic Engineering, Human Phenome Institute, School of Life Sciences, Fudan University, Shanghai, 200438, China; Fudan University Taizhou Institute of Health Sciences, Taizhou, Jiangsu 225312, China; Department of Clinical Laboratory, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital Affiliated to School of Medicine, Tongji University, Shanghai, 200081, China; Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, 200030, China; Department of Epidemiology, School of Public Health, The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, 200032, China

Recommended Citation:
Jiang Y.,Man Q.,Liu Z.,et al. Temporal trends in the mortality rate of Alzheimer's disease and other dementias attributable to smoking, 1990–2017[J]. Environmental Research,2020-01-01,184
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