DOI: 10.1016/j.atmosenv.2020.117355
论文题名: Characteristics and potential inhalation exposure risks of PM2.5–bound environmental persistent free radicals in Nanjing, a mega–city in China
作者: Guo X. ; Zhang N. ; Hu X. ; Huang Y. ; Ding Z. ; Chen Y. ; Lian H.-Z.
刊名: Atmospheric Environment
ISSN: 1352-2310
出版年: 2020
卷: 224 语种: 英语
英文关键词: Biological organs
; Free radicals
; Health risks
; Organic pollutants
; Oxidative stress
; Oxygen
; Transition metals
; Air pollutants
; Healthy persons
; Inhalation exposure
; Limited information
; Potential health risks
; Temporal variation
; Toxic elements
; Weak correlation
; Reactive oxygen species
; cadmium
; carbon monoxide
; chromium
; copper
; dissolved oxygen
; free radical
; iron
; manganese
; nickel
; nitrous oxide
; ozone
; reactive oxygen metabolite
; sulfur oxide
; vanadium
; zinc
; free radical
; megacity
; organic pollutant
; oxidative stress
; particle size
; particulate matter
; pollution exposure
; public health
; reactive oxygen species
; temporal variation
; air pollutant
; Article
; China
; city
; concentration (parameter)
; controlled study
; electron transport
; environmental exposure
; half life time
; health hazard
; human
; oxidative stress
; particle size
; particulate matter
; priority journal
; room temperature
; simulation
; Nanjing [Jiangsu]
学科: Half–life
; Inhalation exposure
; Oxidative stress
; Reactive oxygen species
; Temporal variation
中文摘要: PM2.5–bound toxic elements and organic pollutants have been extensively investigated, while limited information is available for environmental persistent free radicals (EPFRs) associated with PM2.5, which may lead to oxidative stress in the human lung when exposed to PM2.5. In this study, the levels and types of PM2.5–bound EPFRs present in Nanjing, a mega–city in China, were analyzed. PM2.5–bound EPFRs were found to mainly be a mixture of carbon– and oxygen–centered radicals. The concentration of PM2.5–bound EPFRs ranged from 2.78 × 1012 to 1.72 × 1013 spins m−3, with an average value of 7.61 × 1012 spins m−3. The half–life of the PM2.5–bound EPFRs was calculated to be an average of 83.5 days when stored at room temperature, with only weak correlations observed between EPFRs and conventional air pollutants (NO2, O3, CO and PM2.5)/PM2.5–bound transition metals (Cu, Zn, Cr, Mn, V, Cd, and Ni) and significant correlations between EPFRs and SO2/PM2.5–bound Fe. PM2.5–bound EPFRs can induce the formation of reactive oxygen species (ROS) in both water and a H2O2 solution, which are used to simulate lung solution of a healthy person and patient, respectively. Therefore, PM2.5–bound EPFRs can lead to potential oxidative stress in humans. Overall, PM2.5–bound EPFRs show an obvious temporal variation and can pose potential health risks to humans via the induction of ROS in the lung solution. © 2020 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/160908
Appears in Collections: 气候变化与战略
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作者单位: State Key Laboratory of Analytical Chemistry for Life Science, Centre of Materials Analysis and School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210023, China; School of Environmental Science & Engineering, Nanjing Tech University, 30 Puzhu Southern Road, Nanjing, 211816, China
Recommended Citation:
Guo X.,Zhang N.,Hu X.,et al. Characteristics and potential inhalation exposure risks of PM2.5–bound environmental persistent free radicals in Nanjing, a mega–city in China[J]. Atmospheric Environment,2020-01-01,224