globalchange  > 气候变化与战略
DOI: 10.1073/pnas.2007366117
论文题名:
The UBC27–AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis
作者: Pan W.; Lin B.; Yang X.; Liu L.; Xia R.; Li J.; Wu Y.; Xie Q.
刊名: Proceedings of the National Academy of Sciences of the United States of America
ISSN: 0027-8424
出版年: 2020
卷: 117, 期:44
起始页码: 27694
结束页码: 27702
语种: 英语
英文关键词: ABA ; ABI1 ; Drought response ; Ubiquitin conjugating enzyme ; Ubiquitination
英文摘要: Abscisic acid (ABA) is the key phytohormone in plant drought tolerance and stress adaptation. The clade A protein phosphatase 2Cs (PP2Cs) like ABI1 (ABA-INSENSITIVE 1) work as coreceptors of ABA and regulate multiple ABA responses. Ubiquitination of ABI1 has been proven to play important regulatory roles in ABA signaling. However, the specific ubiquitin conjugating enzyme (E2) involved is unknown. Here, we report that UBC27 is an active E2 that positively regulates ABA signaling and drought tolerance. UBC27 forms the E2-E3 pair with the drought regulator RING E3 ligase AIRP3. Both UBC27 and AIRP3 interact with ABI1 and affect the ubiquitination and degradation of ABI1. ABA activates the expression of UBC27, inhibits the proteasome degradation of UBC27, and enhances the interaction between UBC27 and ABI1 to increase its activity. These findings uncover a regulatory mechanism in ABA signaling and drought response and provide a further understanding of the plant ubiquitination system and ABA signaling pathway. © 2020 National Academy of Sciences. All rights reserved.
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/163369
Appears in Collections:气候变化与战略

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作者单位: Pan, W., State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China, College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China; Lin, B., State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China, College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China; Yang, X., State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China; Liu, L., School of Life Sciences, Shandong University, Qingdao, Shandong 266237, China; Xia, R., State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China; Li, J., State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China; Wu, Y., State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China; Xie, Q., State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China, College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China

Recommended Citation:
Pan W.,Lin B.,Yang X.,et al. The UBC27–AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis[J]. Proceedings of the National Academy of Sciences of the United States of America,2020-01-01,117(44)
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