globalchange  > 气候变化与战略
DOI: 10.1073/pnas.2018123117
论文题名:
Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation
作者: Li K.; Zhang S.; Song X.; Weyrich A.; Wang Y.; Liu X.; Wan N.; Liu J.; Lovy M.; Cui H.; Frenkel V.; Titievsky A.; Panov J.; Brodsky L.; Nevo E.
刊名: Proceedings of the National Academy of Sciences of the United States of America
ISSN: 0027-8424
出版年: 2020
卷: 117, 期:51
起始页码: 32499
结束页码: 32508
语种: 英语
英文关键词: Genomic sequencing ; Methylation ; Repeatome ; Speciation models ; Subterranean rodents
Scopus关键词: protein p53 ; animal experiment ; Article ; climate warming ; cold ; copy number variation ; DNA repair ; evolution ; gene ; gene cluster ; genomic island ; hypoxia ; mole rat ; nonhuman ; Pleistocene ; population size ; priority journal ; rat ; separation technique ; sequence analysis ; signal transduction ; single nucleotide polymorphism ; species differentiation ; thermoregulation
英文摘要: Speciation mechanisms remain controversial. Two speciation models occur in Israeli subterranean mole rats, genus Spalax: a regional speciation cline southward of four peripatric climatic chromosomal species and a local, geologic-edaphic, genic, and sympatric speciation. Here we highlight their genome evolution. The five species were separated into five genetic clusters by single nucleotide polymorphisms, copy number variations (CNVs), repeatome, and methylome in sympatry. The regional interspecific divergence correspond to Pleistocene climatic cycles. Climate warmings caused chromosomal speciation. Triple effective population size, Ne, declines match glacial cold cycles. Adaptive genes evolved under positive selection to underground stresses and to divergent climates, involving interspecies reproductive isolation. Genomic islands evolved mainly due to adaptive evolution involving ancient polymorphisms. Repeatome, including both CNV and LINE1 repetitive elements, separated the five species. Methylation in sympatry identified geologically chalk-basalt species that differentially affect thermoregulation, hypoxia, DNA repair, P53, and other pathways. Genome adaptive evolution highlights climatic and geologic-edaphic stress evolution and the two speciation models, peripatric and sympatric. © 2020 National Academy of Sciences. All rights reserved.
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/163892
Appears in Collections:气候变化与战略

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作者单位: Li, K., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China, Institute of Evolution, University of Haifa, Haifa, 3498838, Israel; Zhang, S., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Song, X., School of Public Health, Lanzhou University, Lanzhou, 730000, China; Weyrich, A., Leibniz Institute for Zoo and Wildlife Research, Berlin, 10315, Germany; Wang, Y., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Liu, X., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Wan, N., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Liu, J., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Lovy, M., Faculty of Science, University of South Bohemia, České Budejovice, 370 05, Czech Republic; Cui, H., Department of Gastroenterology, The 305 Hospital of PLA, Beijing, 100017, China; Frenkel, V., Institute of Evolution, University of Haifa, Haifa, 3498838, Israel; Titievsky, A., Tauber Bioinformatics Research Center, Haifa, 3498838, Israel; Panov, J., Tauber Bioinformatics Research Center, Haifa, 3498838, Israel, Sagol Department of Neurobiology, University of Haifa, Haifa, 3498838, Israel; Brodsky, L., Tauber Bioinformatics Research Center, Haifa, 3498838, Israel; Nevo, E., Institute of Evolution, University of Haifa, Haifa, 3498838, Israel

Recommended Citation:
Li K.,Zhang S.,Song X.,et al. Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation[J]. Proceedings of the National Academy of Sciences of the United States of America,2020-01-01,117(51)
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