globalchange  > 气候变化与战略
DOI: 10.1016/j.scib.2020.07.027
论文题名:
Charting brain growth in tandem with brain templates at school age
作者: Dong H.-M.; Castellanos F.X.; Yang N.; Zhang Z.; Zhou Q.; He Y.; Zhang L.; Xu T.; Holmes A.J.; Thomas Yeo B.T.; Chen F.; Wang B.; Beckmann C.; White T.; Sporns O.; Qiu J.; Feng T.; Chen A.; Liu X.; Chen X.; Weng X.; Milham M.P.; Zuo X.-N.
刊名: Science Bulletin
ISSN: 20959273
出版年: 2020
卷: 65, 期:22
起始页码: 1924
结束页码: 1934
语种: 英语
中文关键词: Brain templates ; Development ; Ethnicity ; Growth charts ; Neuroimaging
英文关键词: Cost benefit analysis ; Cost functions ; Graphic methods ; Magnetic resonance imaging ; Neuroimaging ; Pediatrics ; Brain networks ; Brain templates ; Chart analysis ; Children and adolescents ; Parietal areas ; Pediatric MRI ; Shape analysis ; Volumetric growth ; Population statistics
英文摘要: Brain growth charts and age-normed brain templates are essential resources for researchers to eventually contribute to the care of individuals with atypical developmental trajectories. The present work generates age-normed brain templates for children and adolescents at one-year intervals and the corresponding growth charts to investigate the influences of age and ethnicity using a common pediatric neuroimaging protocol. Two accelerated longitudinal cohorts with the identical experimental design were implemented in the United States and China. Anatomical magnetic resonance imaging (MRI) of typically developing school-age children (TDC) was obtained up to three times at nominal intervals of 1.25 years. The protocol generated and compared population- and age-specific brain templates and growth charts, respectively. A total of 674 Chinese pediatric MRI scans were obtained from 457 Chinese TDC and 190 American pediatric MRI scans were obtained from 133 American TDC. Population- and age-specific brain templates were used to quantify warp cost, the differences between individual brains and brain templates. Volumetric growth charts for labeled brain network areas were generated. Shape analyses of cost functions supported the necessity of age-specific and ethnicity-matched brain templates, which was confirmed by growth chart analyses. These analyses revealed volumetric growth differences between the two ethnicities primarily in lateral frontal and parietal areas, regions which are most variable across individuals in regard to their structure and function. Age- and ethnicity-specific brain templates facilitate establishing unbiased pediatric brain growth charts, indicating the necessity of the brain charts and brain templates generated in tandem. These templates and growth charts as well as related codes have been made freely available to the public for open neuroscience (https://github.com/zuoxinian/CCS/tree/master/H3/GrowthCharts). © 2020 Science China Press
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/169879
Appears in Collections:气候变化与战略

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作者单位: Research Center for Lifespan Development of Brain and Mind, Institute of Psychology, Chinese Academy of Sciences (CAS), Beijing, 100101, China; State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, 100875, China; Department of Child and Adolescent Psychiatry, New York University School of Medicine, New York, NY 10016, United States; Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, NY 10962, United States; Department of Psychology, University of CAS, Beijing, 100049, China; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, United States; Child Mind Institute, New York, NY 10022, United States; Department of Psychology, Yale University, New Haven, CT 06511, United States; Department of Electrical and Computer Engineering, Clinical Imaging Research Centre, N.1 Institute for Health and Memory Networks Program, National University of Singapore, Singapore, 117574, Singapore; Department of Physics, Zhejiang University, Hangzhou, 310058, China; Binzhou Medical University, Yantai, 264100, China; Donders Institute, Radboud University Medical Centre, Nijmegen, 6525 EN, Netherlands; Department of Child and Adolescent Psychiatry, Erasmus University, Rotterdam, 3000 CB, Netherlands; Department of Radiology, Erasmus University Medical Centre, Rotterdam, 3000 CA, Netherlands; School of Psychology, Southwest University, Chongqing, 400715, China; Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, 510631, China; Institute of Children Health, Changzhou Children's Hospital, Changzhou, 213003, China; Key Laboratory of Brain and Education, School of Education Science, Nanning Normal University, Nanning, 530001, China; CAS Key Laboratory of Behavioral Science, Institute of Psychology, Beijing, 100101, China; IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, 100875, China

Recommended Citation:
Dong H.-M.,Castellanos F.X.,Yang N.,et al. Charting brain growth in tandem with brain templates at school age[J]. Science Bulletin,2020-01-01,65(22)
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