globalchange  > 气候变化与战略
DOI: 10.1016/j.scib.2020.12.025
论文题名:
Inactivating SARS-CoV-2 by electrochemical oxidation
作者: Tu Y.; Tang W.; Yu L.; Liu Z.; Liu Y.; Xia H.; Zhang H.; Chen S.; Wu J.; Cui X.; Zhang J.; Wang F.; Hu Y.; Deng D.
刊名: Science Bulletin
ISSN: 20959273
出版年: 2021
卷: 66, 期:7
起始页码: 720
结束页码: 726
语种: 英语
中文关键词: Electrochemical oxidation ; Reactive oxygen species ; Receptor binding domain ; SARS-CoV-2
英文关键词: Anodes ; Biohazards ; Disinfection ; Electrochemical oxidation ; Electrolytes ; Mass spectrometry ; Nickel oxide ; Peptides ; Sodium Carbonate ; Sodium compounds ; Viruses ; Wastewater treatment ; Anode catalysts ; Disinfection efficiency ; Mass spectrometry analysis ; Nickel oxide hydroxides ; Peptide backbones ; Receptor-binding domains ; Theoretical calculations ; Virus transmission ; Diseases
英文摘要: Fully inactivating SARS-CoV-2, the virus causing coronavirus disease 2019, is of key importance for interrupting virus transmission but is currently performed by using biologically or environmentally hazardous disinfectants. Herein, we report an eco-friendly and efficient electrochemical strategy for inactivating the SARS-CoV-2 using in-situ formed nickel oxide hydroxide as anode catalyst and sodium carbonate as electrolyte. At a voltage of 5 V, the SARS-CoV-2 viruses can be rapidly inactivated with disinfection efficiency reaching 95% in only 30 s and 99.99% in 5 min. Mass spectrometry analysis and theoretical calculations indicate that the reactive oxygen species generated on the anode can oxidize the peptide chains and induce cleavage of the peptide backbone of the receptor binding domain of the SARS-CoV-2 spike glycoprotein, and thereby disables the virus. This strategy provides a sustainable and highly efficient approach for the disinfection of the SARS-CoV-2 viruliferous aerosols and wastewater. © 2020 Science China Press
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/170411
Appears in Collections:气候变化与战略

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作者单位: State Key Laboratory of Catalysis, Collaborative Innovation Center of Chemistry for Energy Materials, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; University of Chinese Academy of Sciences, Beijing, 100049, China; College of Materials Science and Engineering, Zhengzhou University, Zhengzhou, 450001, China; Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China

Recommended Citation:
Tu Y.,Tang W.,Yu L.,et al. Inactivating SARS-CoV-2 by electrochemical oxidation[J]. Science Bulletin,2021-01-01,66(7)
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