全球变化知识资源中心

Knowledge Resources Center for Global Change


Email:
Passwd
验证:
	换一张
Have you forgotten your password? Stay signed in Log In

globalchange > 过去全球变化的重建

DOI:	10.1371/journal.pone.0130659
论文题名:	The Biogeography of Putative Microbial Antibiotic Production
作者:	Hélène Morlon; Timothy K. O'Connor; Jessica A. Bryant; Louise K. Charkoudian; Kathryn M. Docherty; Evan Jones; Steven W. Kembel; Jessica L. Green; Brendan J. M. Bohannan
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2015
发表日期:	2015-6-23
卷:	10, 期:6
语种:	英语
英文关键词:	Phylogenetics ; Biogeography ; Antibiotics ; Sequence databases ; Phylogeography ; Phylogenetic analysis ; Sequence analysis ; Environmental geography
英文摘要:	Understanding patterns in the distribution and abundance of functional traits across a landscape is of fundamental importance to ecology. Mapping these distributions is particularly challenging for species-rich groups with sparse trait measurement coverage, such as flowering plants, insects, and microorganisms. Here, we use likelihood-based character reconstruction to infer and analyze the spatial distribution of unmeasured traits. We apply this framework to a microbial dataset comprised of 11,732 ketosynthase alpha gene sequences extracted from 144 soil samples from three continents to document the spatial distribution of putative microbial polyketide antibiotic production. Antibiotic production is a key competitive strategy for soil microbial survival and performance. Additionally, novel antibiotic discovery is highly relevant to human health, making natural antibiotic production by soil microorganisms a major target for bioprospecting. Our comparison of trait-based biogeographical patterns to patterns based on taxonomy and phylogeny is relevant to our basic understanding of microbial biogeography as well as the pressing need for new antibiotics.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0130659&type=printable
Citation statistics:
资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/22393
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

Files in This Item:	Download All

File Name/ File Size	Content Type	Version	Access	License
journal.pone.0130659.PDF（1362KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Institut de Biologie, UMR CNRS 8197, Ecole Normale Supérieure, Paris, France;Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America;Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America;Department of Chemistry, Haverford College, Haverford, Pennsylvania, United States of America;Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan, United States of America;Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon, United States of America;Département des sciences biologiques, Université du Québec à Montréal, Montréal, Québec, Canada;Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon, United States of America;Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon, United States of America

Recommended Citation:

Hélène Morlon,Timothy K. O'Connor,Jessica A. Bryant,et al. The Biogeography of Putative Microbial Antibiotic Production[J]. PLOS ONE,2015-01-01,10(6)

Service
	Recommend this item
	Sava as my favorate item
	Show this item's statistics
	Export Endnote File
Google Scholar
	Similar articles in Google Scholar
	[Hélène Morlon]'s Articles
	[Timothy K. O'Connor]'s Articles
	[Jessica A. Bryant]'s Articles
百度学术
	Similar articles in Baidu Scholar
	[Hélène Morlon]'s Articles
	[Timothy K. O'Connor]'s Articles
	[Jessica A. Bryant]'s Articles
CSDL cross search
	Similar articles in CSDL Cross Search
	[Hélène Morlon]‘s Articles
	[Timothy K. O'Connor]‘s Articles
	[Jessica A. Bryant]‘s Articles
Related Copyright Policies
Null
收藏/分享