globalchange  > 过去全球变化的重建
DOI: 10.1371/journal.pone.0148669
论文题名:
Quantification of Influenza Virus RNA in Aerosols in Patient Rooms
作者: Nancy H. L. Leung; Jie Zhou; Daniel K. W. Chu; Han Yu; William G. Lindsley; Donald H. Beezhold; Hui-Ling Yen; Yuguo Li; Wing-Hong Seto; Joseph S. M. Peiris; Benjamin J. Cowling
刊名: PLOS ONE
ISSN: 1932-6203
出版年: 2016
发表日期: 2016-2-5
卷: 11, 期:2
语种: 英语
英文关键词: Influenza viruses ; Influenza A virus ; Humidity ; Influenza ; RNA viruses ; Respiratory infections ; Aerosols ; Influenza B virus
英文摘要: Background The potential for human influenza viruses to spread through fine particle aerosols remains controversial. The objective of our study was to determine whether influenza viruses could be detected in fine particles in hospital rooms. Methods and Findings We sampled the air in 2-bed patient isolation rooms for four hours, placing cyclone samplers at heights of 1.5m and 1.0m. We collected ten air samples each in the presence of at least one patient with confirmed influenza A virus infection, and tested the samples by reverse transcription polymerase chain reaction. We recovered influenza A virus RNA from 5/10 collections (50%); 4/5 were from particles>4 μm, 1/5 from 1–4 μm, and none in particles<1 μm. Conclusions Detection of influenza virus RNA in aerosols at low concentrations in patient rooms suggests that healthcare workers and visitors might have frequent exposure to airborne influenza virus in proximity to infected patients. A limitation of our study was the small sample size. Further studies should be done to quantify the concentration of viable influenza virus in healthcare settings, and factors affecting the detection of influenza viruses in fine particles in the air.
URL: http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0148669&type=printable
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/24106
Appears in Collections:过去全球变化的重建
影响、适应和脆弱性
科学计划与规划
气候变化与战略
全球变化的国际研究计划
气候减缓与适应
气候变化事实与影响

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作者单位: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;Centre of Influenza Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;Centre of Influenza Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;Allergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, United States of America;Allergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, United States of America;WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;Centre of Influenza Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;Centre of Influenza Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China;WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China

Recommended Citation:
Nancy H. L. Leung,Jie Zhou,Daniel K. W. Chu,et al. Quantification of Influenza Virus RNA in Aerosols in Patient Rooms[J]. PLOS ONE,2016-01-01,11(2)
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