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DOI:	10.1371/journal.pone.0173945
论文题名:	A screening questionnaire for convulsive seizures: A three-stage field-validation in rural Bolivia
作者:	Loretta Giuliano; Calogero Edoardo Cicero; Elizabeth Blanca Crespo Gómez; Sandra Padilla; Elisa Bruno; Mario Camargo; Benoit Marin; Vito Sofia; Pierre-Marie Preux; Marianne Strohmeyer; Alessandro Bartoloni; Alessandra Nicoletti
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2017
发表日期:	2017-3-16
卷:	12, 期:3
语种:	英语
英文关键词:	Epilepsy ; Health screening ; Rural areas ; Tonic-clonic seizures ; Bolivia ; Questionnaires ; Confidence intervals ; Language
英文摘要:	Introduction Epilepsy is one of the most common neurological diseases in Latin American Countries (LAC) and epilepsy associated with convulsive seizures is the most frequent type. Therefore, the detection of convulsive seizures is a priority, but a validated Spanish-language screening tool to detect convulsive seizures is not available. We performed a field validation to evaluate the accuracy of a Spanish-language questionnaire to detect convulsive seizures in rural Bolivia using a three-stage design. The questionnaire was also administered face-to-face, using a two-stage design, to evaluate the difference in accuracy. Methods The study was carried out in the rural communities of the Gran Chaco region. The questionnaire consists of a single screening question directed toward the householders and a confirmatory section administered face-to-face to the index case. Positive subjects underwent a neurological examination to detect false positive and true positive subjects. To estimate the proportion of false negative, a random sample of about 20% of the screened negative underwent a neurological evaluation. Results 792 householders have been interviewed representing a population of 3,562 subjects (52.2% men; mean age 24.5 ± 19.7 years). We found a sensitivity of 76.3% (95% CI 59.8–88.6) with a specificity of 99.6% (95% CI 99.4–99.8). The two-stage design showed only a slightly higher sensitivity respect to the three-stage design. Conclusion Our screening tool shows a good accuracy and can be easily used by trained health workers to quickly screen the population of the rural communities of LAC through the householders using a three-stage design.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0173945&type=printable
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资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/25795
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

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作者单位:

Department of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, Section of Neurosciences, University of Catania, Catania, Italy;Department of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, Section of Neurosciences, University of Catania, Catania, Italy;Hospital Universitario Hernández Vera, Santa Cruz, Bolivia;Center of Anthropological Researches of the Teko Guaraní, Gutierrez, Bolivia;Department of Neurology, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom;The Bolivian League Against Epilepsy, Santa Cruz, Bolivia;INSERM, U1094, Tropical Neuroepidemiology, Limoges, France;Department of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, Section of Neurosciences, University of Catania, Catania, Italy;INSERM, U1094, Tropical Neuroepidemiology, Limoges, France;Department of Experimental and Clinical Medicine, Infectious and Tropical Diseases Unit, University of Florence, Florence, Italy;Department of Experimental and Clinical Medicine, Infectious and Tropical Diseases Unit, University of Florence, Florence, Italy;Department of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, Section of Neurosciences, University of Catania, Catania, Italy

Recommended Citation:

Loretta Giuliano,Calogero Edoardo Cicero,Elizabeth Blanca Crespo Gómez,et al. A screening questionnaire for convulsive seizures: A three-stage field-validation in rural Bolivia[J]. PLOS ONE,2017-01-01,12(3)

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