DOI: 10.1016/j.jcou.2017.01.024
Scopus记录号: 2-s2.0-85013276118
论文题名: Extraction of total alkaloids, peimine and peiminine from the flower of Fritillaria thunbergii Miq using supercritical carbon dioxide
作者: Ruan X. ; Cui W.-X. ; Yang L. ; Li Z.-H. ; Liu B. ; Wang Q.
刊名: Journal of CO2 Utilization
ISSN: 22129820
出版年: 2017
卷: 18 语种: 英语
英文关键词: Antioxidant activities
; Central composite design
; Fritillaria thunbergii Miq
; Peimine
; Peiminine
; Supercritical fluid extraction
; Total alkaloids
Scopus关键词: Agents
; Alkaloids
; Antioxidants
; Carbon
; Carbon dioxide
; Effluent treatment
; Ethanol
; Extraction
; Metabolites
; Organic solvents
; Plants (botany)
; Supercritical fluids
; Anti-oxidant activities
; Central composite designs
; Fritillaria
; Peimine
; Peiminine
; Supercritical fluid extraction
英文摘要: Graphical abstract: This study for the first time designed to use supercritical fluid extraction (SFE) to extract total alkaloids, peimine and peiminine from the flower of Fritillaria thunbergii Miq. 2,2′-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) diammonium salt radical cation scavenging activity (ABTS-RSA) and ferric reducing antioxidant potential (FRAP) assay were selected to evaluate the antioxidant capacity of the extracts. A central composite design (CCD) with four variables (extract time (1.5-3.5) h, temperature (50-70)°C, pressure (15-35) MPa and co-solvent (ethanol: water) ratio (80-100, v/v) %was employed for optimization of process parameters, and response surface plots were constructed in accordance with a second order polynomial model. The highest yields of total alkaloids (2.9mg/g), peimine (0.7mg/g) and peiminine (0.07mg/g) were predicted at optimal conditions of 2.9h, 61.3°C, 30.6MPa and 90.3% ethanol and the antioxidant activity of the extracts was estimated to be comparable to that of α-tocopherol with ABTS value of 0.5mg/mL and FRAP value of 658mg AAE/100g, respectively. These results suggest that optimization of the extraction conditions is critical for accurate quantification of total alkaloids, peimine and peiminine, and antioxidants in F. thunbergii Miq flower, which may further be used for industrial extraction procedure. © 2017 Elsevier Ltd. 资助项目: National Natural Science Foundation of China
Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/52760
Appears in Collections: 影响、适应和脆弱性
There are no files associated with this item.
Recommended Citation:
Ruan X.,Cui W.-X.,Yang L.,et al. Extraction of total alkaloids, peimine and peiminine from the flower of Fritillaria thunbergii Miq using supercritical carbon dioxide[J]. Journal of CO2 Utilization,2017-01-01,18