DOI: 10.1016/j.tree.2015.10.003
论文题名: An Individual-Centered Framework For Unravelling Genotype-Phenotype Interactions
作者: Baguette M. ; Legrand D. ; Stevens V.M.
刊名: Trends in Ecology and Evolution
ISSN: 1695347
出版年: 2015
卷: 30, 期: 12 起始页码: 709
结束页码: 711
语种: 英语
英文关键词: Epigenome
; Genome
; Molecular pedigree of evolutionary changes
; Phenome
; Proteome
; Syndrome
Scopus关键词: biological model
; genetic variability
; genotype
; human
; inheritance
; phenotype
; physiology
; procedures
; statistical analysis
; systems biology
; Data Interpretation, Statistical
; Genetic Variation
; Genotype
; Humans
; Inheritance Patterns
; Models, Biological
; Phenotype
; Systems Biology
英文摘要: A new framework in which the multiple levels of molecular variations contribute to phenotypic variations in a complex, nonlinear and interactive way, challenges the hierarchical nature of the relationships between the genotypic and phenotypic spaces. This individual-centered framework provides new insights on the evolutionary mechanisms involved in the production of phenotypes. We propose to move this research agenda forward by combining selection experiments and functional genetics. © 2015 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/67120
Appears in Collections: 全球变化的国际研究计划 气候变化与战略
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作者单位: Station d'Ecologie Expérimentale, CNRS USR 2936, Moulis, France; Muséum National d'Histoire Naturelle, UMR 7205 ISYEB, Paris, France; Earth and Life Institute, UCL BRC, Louvain-la-Neuve, Belgium
Recommended Citation:
Baguette M.,Legrand D.,Stevens V.M.. An Individual-Centered Framework For Unravelling Genotype-Phenotype Interactions[J]. Trends in Ecology and Evolution,2015-01-01,30(12)