| DOI: | 10.1016/j.tree.2014.07.004
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| 论文题名: | The changing face of the molecular evolutionary clock |
| 作者: | Ho S.Y.W.
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| 刊名: | Trends in Ecology and Evolution
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| ISSN: | 1695347
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| 出版年: | 2014
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| 卷: | 29, 期:9 | | 起始页码: | 496
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| 结束页码: | 503
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| 语种: | 英语
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| 英文关键词: | Genomic data
; Molecular clock
; Pacemaker models
; Phylogenetic analysis
; Rate heterogeneity
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| Scopus关键词: | evolutionary biology
; genomics
; heterogeneity
; molecular ecology
; phylogenetics
; timescale
; biological model
; DNA sequence
; genetic drift
; genomics
; molecular evolution
; mutation rate
; phylogeny
; Evolution, Molecular
; Genetic Drift
; Genomics
; Models, Genetic
; Mutation Rate
; Phylogeny
; Sequence Analysis, DNA
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| 英文摘要: | The molecular clock has played an important role in biological research, both as a description of the evolutionary process and as a tool for inferring evolutionary timescales. Genomic data have provided valuable insights into the molecular clock, allowing the patterns and causes of evolutionary rate variation to be characterized in increasing detail. I explain how genome sequences offer exciting opportunities for estimating the timescale of the Tree of Life. I describe the different approaches that have been used to deal with the computational and statistical challenges encountered in molecular clock analyses of genomic data. Finally, I offer a perspective on the future of molecular clocks, highlighting some of the key limitations and the most promising research directions. © 2014 Elsevier Ltd. |
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| 资源类型: | 期刊论文
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/67326
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| Appears in Collections: | 全球变化的国际研究计划
气候变化与战略
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作者单位: | School of Biological Sciences, University of Sydney, Sydney, NSW, Australia
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| Recommended Citation: | |
Ho S.Y.W.. The changing face of the molecular evolutionary clock[J]. Trends in Ecology and Evolution,2014-01-01,29(9)
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