DOI: 10.1016/j.atmosenv.2013.11.047
Scopus记录号: 2-s2.0-84908339843
论文题名: Physicochemical properties and ability to generate free radicals of ambient coarse, fine, and ultrafine particles in the atmosphere of Xuanwei, China, an area of high lung cancer incidence
作者: Lu S ; , Yi F ; , Hao X ; , Yu S ; , Ren J ; , Wu M ; , Jialiang F ; , Yonemochi S ; , Wang Q
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2014
卷: 97 起始页码: 519
结束页码: 528
语种: 英语
英文关键词: Chemical elements
; China
; Free radicals
; Oxidative potential
; Size-resolved ambient particles
; Xuanwei
Scopus关键词: Free radicals
; Ambient particles
; China
; Lung Cancer
; Oxidative potential
; Physicochemical property
; Ultrafine particle
; Xuanwei
; Chemical elements
; calcium
; chromium
; coal
; copper
; free radical
; iron
; lead
; manganese
; mineral
; nickel
; silicon
; titanium
; trace metal
; zinc
; ambient air
; atmospheric chemistry
; cancer
; combustion
; disease incidence
; disease prevalence
; free radical
; indoor air
; particle size
; particulate matter
; physicochemical property
; pollution exposure
; risk factor
; soot
; trace metal
; air pollutant
; air pollution
; ambient air
; analytic method
; Article
; cancer incidence
; cell free system
; China
; combustion
; controlled study
; electron spin resonance
; energy dispersive X ray detection
; fly ash
; human
; lung cancer
; oxidation
; particle induced X ray emission
; particle size
; particulate matter
; physical chemistry
; scanning electron microscopy
; soot
; spring
; winter
; China
; China
; Xuanwei
; Yunnan
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: The link between the high incidence of lung cancer and harmful pollutants emitted by local coal combustion in Xuanwei, Yunnan province, China, has been a focus of study since the 1980s. However, the mechanisms responsible for the high lung cancer rate remain unclear, necessitating further study. Since a close relationship between ambient air particle pollution and respiratory diseases exists, we sampled size-resolved ambient particles from the atmosphere of Xuanwei. In our indoor experiment, cutting-edge methods, including scanning electron microscopy coupled with energy dispersive X-ray detection (SEM/EDX), particle-induced X-ray emission (PIXE), electronic paramagnetic resonance (EPR) and the cell-free DCFH-DA assay, were employed to investigate the physicochemical properties, the potential to generate free radicals and the oxidative potential of ambient coarse (diameter, 1.8-10μm), fine (diameter, 0.1-1.8μm), and ultrafine (diameter, <0.1μm) particles. We found the total mass concentrations of the size-resolved particles collected in spring were higher than that in early winter. Mass percentage of fine particles accounted for 68% and 61% of the total particulate mass in spring and in early winter samples, respectively, indicating that fine particles were the major component of the Xuanwei ambient particulate matters. On the other hand, the results of SEM/EDX analysis showed that the coarse particles were dominated by minerals, the fine particles by soot aggregates and fly ashes, and the ultrafine particles by soot particles and unidentified particles. Our PIXE results revealed that crustal elements (Ca, Ti Si, Fe) were mainly distributed in coarse particles, while trace metals (Cr, Mn, Ni, Cu, Zn, Pb) dominated in the fine particle fraction, and S, a typical element emitted by coal combustion, mainly resided in fine particles collected from the winter atmosphere. EPR results indicated that the magnitude of free radical intensity caused by size-resolved particles followed these patterns: fine particles>coarse particles>ultrafine particles for spring samples and ultrafine particles>fine particles>coarse particles for winter samples. Cell-free DCFH assay results conclusively showed that all of the measured particle suspensions displayed a higher oxidative potential than the negative control. The correlation coefficient (R2) between free radical intensity and fluorescent intensity generated by the size-resolved particles was 0.535 and 0.507 for the spring and winter seasons, respectively, implying that ambient air particles in the Xuanwei atmosphere have the ability to generate free radicals, and fine and ultrafine particles could be hazardous to local residents. © 2013 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/80635
Appears in Collections: 气候变化事实与影响
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作者单位: School of Environmental and Chemical Engineering, Shanghai University, Shanghai, China; Institute for Environmental Pollution and Health, Shanghai University, Shanghai, China; Center for Environmental Science in Saitama, Saitama, Japan; School of Science and Engineering, Saitama University, Saitama, Japan
Recommended Citation:
Lu S,, Yi F,, Hao X,et al. Physicochemical properties and ability to generate free radicals of ambient coarse, fine, and ultrafine particles in the atmosphere of Xuanwei, China, an area of high lung cancer incidence[J]. Atmospheric Environment,2014-01-01,97