DOI: 10.1016/j.atmosenv.2015.08.043
Scopus记录号: 2-s2.0-84939810548
论文题名: Pulmonary inflammatory effects of source-oriented particulate matter from California's San Joaquin Valley
作者: Plummer L ; E ; , Carosino C ; M ; , Bein K ; J ; , Zhao Y ; , Willits N ; , Smiley-Jewell S ; , Wexler A ; S ; , Pinkerton K ; E
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2015
卷: 119 起始页码: 174
结束页码: 181
语种: 英语
英文关键词: Air pollution
; Fresno
; PM
; Submicron fine
; Ultrafine
Scopus关键词: Air pollution
; Amphibious vehicles
; Crashworthiness
; Emission control
; Particle size
; Particulate emissions
; Promethium
; Regulatory compliance
; Toxicity
; Ambient particulate Matter
; Biochemical indicators
; Bronchoalveolar lavage fluid
; Chemical compositions
; Fresno
; Physicochemical property
; Submicron
; Ultrafine
; Compliance control
; abnormality
; ambient air
; atmospheric pollution
; bioindicator
; concentration (composition)
; dose-response relationship
; emission control
; emission inventory
; environmental legislation
; health impact
; particle size
; particulate matter
; physicochemical property
; pollutant source
; pollution exposure
; rodent
; spatiotemporal analysis
; toxicity
; air pollution control
; ambient air
; animal experiment
; animal model
; Article
; aspiration
; atmosphere
; biomass
; combustion
; controlled study
; environmental exposure
; lung lavage
; male
; mouse
; nonhuman
; oropharynx
; particle size
; particulate matter
; pneumonia
; priority journal
; summer
; winter
; California
; Fresno [California]
; San Joaquin Valley
; United States
; Mus
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: The EPA regulates ambient particulate matter (PM) because substantial associations have been established between PM and health impacts. Presently, regulatory compliance involves broad control of PM emission sources based on mass concentration rather than chemical composition, although PM toxicity is likely to vary depending upon PM physicochemical properties. The overall objective of this study was to help inform source-specific PM emission control regulations. For the first time, source-oriented PM was collected from the atmosphere in Fresno, CA, onto 38 source/size substrates. Mice were exposed via oropharyngeal aspiration to equivalent mass doses [50 μg] of two size fractions: ultrafine (Dp < 0.17 μm) and submicron fine (0.17 < Dp < 1 μm) during summer and winter seasons. At 24 h post-exposure, cellular and biochemical indicators of pulmonary inflammation were evaluated in the bronchoalveolar lavage fluid. Significant inflammatory responses were elicited by vehicle, regional background, and cooking PM sources that were dependent on season and particle size. This is the first study of source-oriented toxicity of atmospheric PM and supports source-specific emissions control strategies. © 2015. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/81538
Appears in Collections: 气候变化事实与影响
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作者单位: Center for Health and the Environment, University of California, Davis, One Shields Avenue, Davis, CA, United States; Air Quality Research Center, University of California, Davis, One Shields Avenue, Davis, CA, United States; Department of Statistics, University of California, Davis, One Shields Avenue, Davis, CA, United States
Recommended Citation:
Plummer L,E,, Carosino C,et al. Pulmonary inflammatory effects of source-oriented particulate matter from California's San Joaquin Valley[J]. Atmospheric Environment,2015-01-01,119