DOI: 10.1016/j.marpolbul.2014.04.022
Scopus记录号: 2-s2.0-84906283697
论文题名: Pyrene induces a reduction in midbrain size and abnormal swimming behavior in early-hatched pufferfish larvae
作者: Sugahara Y. ; Kawaguchi M. ; Itoyama T. ; Kurokawa D. ; Tosa Y. ; Kitamura S.-I. ; Handoh I.C. ; Nakayama K. ; Murakami Y.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2014
卷: 85, 期: 2 起始页码: 479
结束页码: 486
语种: 英语
英文关键词: Development
; Heavy oil
; Nervous system
; Phenanthrene
; Pyrene
; Teleosts
Scopus关键词: Anthracene
; Crude oil
; Heavy oil production
; Neurology
; Toxicity
; Development
; Heavy oil
; Heavy oil mixtures
; Larval behavior
; Phenanthrene
; Swimming behavior
; Takifugu rubripes
; Teleosts
; Pyrene
; phenanthrene
; pyrene
; phenanthrene
; phenanthrene derivative
; pyrene
; pyrene derivative
; ecotoxicology
; heavy oil
; larva
; oil spill
; PAH
; pollution effect
; pollution exposure
; pyrene
; swimming behavior
; teleost
; animal behavior
; article
; bioaccumulation
; bioavailability
; biotransformation
; brain function
; brain size
; central nervous system
; concentration (parameters)
; controlled study
; environmental exposure
; heart beat
; heart rate
; heavy metal poisoning
; immunohistochemistry
; larva
; mesencephalon
; motor performance
; nerve cell differentiation
; neurotoxicity
; nonhuman
; ontogeny
; puffer fish
; superior colliculus
; swimming
; anatomy and histology
; animal
; animal behavior
; drug effects
; larva
; mesencephalon
; organ size
; physiology
; swimming
; Tetraodontiformes
; Takifugu rubripes
; Teleostei
; Tetraodontidae
; Animals
; Behavior, Animal
; Larva
; Mesencephalon
; Organ Size
; Phenanthrenes
; Pyrenes
; Swimming
; Tetraodontiformes
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Spills of heavy oil (HO) have an adverse effect on marine life. We have demonstrated previously that exposure to HO by fertilized eggs of the pufferfish (Takifugu rubripes) induces neural disruption and behavioral abnormality in early-hatched larvae. Here, two kinds of polycyclic aromatic hydrocarbons, pyrene and phenanthrene, were selected to examine their toxic effects on larval behavior of another pufferfish species (T. niphobles). Larvae exposed to pyrene or phenanthrene exhibited no abnormalities in morphology. However, those exposed to pyrene but not phenanthrene swam in an uncoordinated manner, although their swimming distance and speed were normal. The optic tectum, a part of the midbrain, of pyrene-exposed larvae did not grow to full size. Thus, these findings are indicated that pyrene might be a contributor to the behavioral and neuro-developmental toxicity, although there is no indication that it is the only compound participating in the toxicity of the heavy oil mixture. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/85306
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Graduate School of Science and Engineering, Ehime University, 2-5 Bunkyo-cho, Matsuyama, Japan; Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, Japan; Misaki Marine Biological Station, The University of Tokyo, 1024 Koajiro, Misaki, Miura, Japan; Center for Marine Environmental Studies (CMES), Ehime University, 2-5 Bunkyo-cho, Matsuyama, Japan; The Futurability Initiatives, Research Institute for Humanity and Nature, 457-4 Motoyama, Kamigamo, Kita-ku, Kyoto, Japan
Recommended Citation:
Sugahara Y.,Kawaguchi M.,Itoyama T.,et al. Pyrene induces a reduction in midbrain size and abnormal swimming behavior in early-hatched pufferfish larvae[J]. Marine Pollution Bulletin,2014-01-01,85(2)