DOI: 10.1016/j.marpolbul.2016.10.032
Scopus记录号: 2-s2.0-85004154129
论文题名: A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis
作者: Zhang J. ; Wang Y. ; Sun K.-M. ; Fang K. ; Tang X.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2016
卷: 113, 期: 2018-01-02 起始页码: 408
结束页码: 413
语种: 英语
英文关键词: Calcium ion (Ca2 +)
; Oxidative stress
; Polybrominated diphenyl ethers (PBDEs)
; Reactive oxygen species (ROS)
; Rotifer
Scopus关键词: Calcium
; Calmodulin
; Damage detection
; Ecosystems
; Enzymes
; Ethers
; Ions
; Marine biology
; Marine pollution
; Oxidative stress
; Oxygen
; Polyacrylates
; Brachionus plicatilis
; Calcium ions
; Decabrominated diphenyl ether
; Persistent organic pollutant (POP)
; Polybrominated diphenyl ether (PBDEs)
; Reactive oxygen species
; Rotifer
; Superoxide dismutases
; Organic pollutants
; 2,2',4,4' tetrabromodiphenyl ether
; calmodulin
; decabromodiphenyl ether
; messenger RNA
; polybrominated diphenyl ether
; superoxide dismutase
; 2,2',4,4'-tetrabromodiphenyl ether
; decabromobiphenyl ether
; diphenyl ether derivative
; reactive oxygen metabolite
; superoxide dismutase
; water pollutant
; bioaccumulation
; cadmium
; invertebrate
; marine ecosystem
; organic pollutant
; oxidative stress
; PBDE
; persistent organic pollutant
; reactive oxygen species
; reproductive status
; toxicity
; analysis of variance
; Article
; Brachionus plicatilis
; bromination
; calcium homeostasis
; calcium signaling
; controlled study
; gas chromatography
; mass spectrometry
; nonhuman
; oxidative stress
; protein expression
; quantitative analysis
; real time polymerase chain reaction
; sea pollution
; animal
; drug effects
; environmental monitoring
; female
; gene expression
; genetics
; metabolism
; oxidative stress
; procedures
; Rotifera
; theoretical model
; toxicity
; water pollutant
; Brachionus plicatilis
; Invertebrata
; Rotifera
; Animals
; Environmental Monitoring
; Female
; Gene Expression
; Halogenated Diphenyl Ethers
; Models, Theoretical
; Oxidative Stress
; Reactive Oxygen Species
; Rotifera
; Superoxide Dismutase
; Water Pollutants, Chemical
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Polybrominated diphenyl ethers (PBDEs) are widely dispersed persistent organic pollutants in the marine ecosystem. However, their toxic mechanisms in marine organisms, especially invertebrates, remain poorly understood. Two common congeners of PBDEs, tetrabrominated diphenyl ether-47 (BDE-47) and decabrominated diphenyl ether-209 (BDE-209), were investigated. Their toxic mechanisms, with a focus on oxidative stress, were examined in rotifer Brachionus plicatilis. Overproduction of reactive oxygen species (ROS) was induced by two PBDEs. The expression of superoxide dismutase (SOD) mRNA was increased, suggesting SOD play a main role in ROS-scavenging. The intercellular concentrations of calcium ([Ca2 +]in) and the expression of calmodulin (CaM) mRNA were increased. This indicates the calcium ion (Ca2 +) signaling channel is involved in PBDEs stress. Further analysis showed that the reproductive system might be the target site for toxicity of PBDEs. Moreover, high value of detection indexes in BDE-47 experimental groups suggested BDE-47 might cause higher oxidative damage than BDE-209 in rotifers. © 2016 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/86617
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Department of Marine Ecology, College of Marine Life Sciences, Ocean University of China, Qingdao, China; The First Institute of Oceanography (FIO), State Oceanic Administration (SOA), Qingdao, China
Recommended Citation:
Zhang J.,Wang Y.,Sun K.-M.,et al. A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis[J]. Marine Pollution Bulletin,2016-01-01,113(2018-01-02)