DOI: 10.1016/j.marpolbul.2016.03.054
Scopus记录号: 2-s2.0-84979463236
论文题名: Metabolic responses of clams, Ruditapes decussatus and Ruditapes philippinarum, to short-term exposure to lead and zinc
作者: Aru V. ; Sarais G. ; Savorani F. ; Engelsen S.B. ; Cesare Marincola F.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2016
卷: 107, 期: 1 起始页码: 292
结束页码: 299
语种: 英语
英文关键词: Bioindicators
; Clams
; Lead
; NMR-based metabolomics
; Pollution
; Zinc
Scopus关键词: Biochemistry
; Biomarkers
; Heavy metals
; Lead
; Metabolism
; Molluscs
; Pollution
; Shellfish
; Zinc
; Clams
; Laboratory conditions
; Metabolomics
; Metal bioaccumulation
; Ruditapes decussatus
; Ruditapes philippinarum
; Sensitive indicator
; Sensitivity and specificity
; Zinc chloride
; lead
; lead nitrate
; zinc
; zinc chloride
; chloride
; lead
; nitric acid derivative
; zinc
; zinc derivative
; bioindicator
; bivalve
; lead
; metabolism
; mollusc
; nuclear magnetic resonance
; pollution exposure
; zinc
; amino acid composition
; animal behavior
; animal tissue
; Article
; bioaccumulation
; biological monitoring
; concentration (parameters)
; controlled study
; environmental exposure
; environmental impact assessment
; environmental stress
; indicator organism
; mass spectrometry
; metabolomics
; microwave radiation
; nonhuman
; pollution monitoring
; proton nuclear magnetic resonance
; Ruditapes
; Ruditapes decussatus
; Ruditapes philippinarum
; animal
; bivalve
; metabolism
; Bivalvia
; Venerupis (Ruditapes) decussatus
; Venerupis (Ruditapes) philippinarum
; Animals
; Bivalvia
; Chlorides
; Lead
; Metabolomics
; Nitrates
; Zinc
; Zinc Compounds
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: This study investigated the effects of 48 h heavy metal exposure upon the metabolic profiles of Ruditapes decussatus and Ruditapes philippinarum using 1H NMR metabolomics. Both species were exposed to increasing concentrations of lead nitrate (10, 40, 60 and 100 μg/L) and zinc chloride (20, 50, 100 and 150 μg/L), under laboratory conditions. ICP-OES analysis was further performed on the clams' samples in order to verify the occurrence of heavy metal bioaccumulation. With respect to the controls, the metabolic profiles of treated R. decussatus exhibited higher levels of organic osmolytes and lower contents of free amino acids. An opposite behavior was shown by R. philippinarum. In terms of heavy metal, the exposure effects were more evident in the case of Pb rather than Zn. These findings show that NMR-based metabolomics has the required sensitivity and specificity for the identification of metabolites that can act as sensitive indicators of contaminant-induced stress. © 2016 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/87058
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Department of Chemical and Geological Sciences, University of Cagliari, S.S. 554 Bivio Sestu, Monserrato (CA), Italy; Departement of Life and Environmental Sciences, University of Cagliari, Via Ospedale 72, Cagliari, Italy; Quality and Technology, Department of Food Science, University of Copenhagen, Rolighedsvej 26, Frederiksberg C, Denmark; Department of Applied Science and Technology (DISAT), Polytechnic University of Turin, Corso Duca degli Abruzzi 24, Torino (TO), Italy
Recommended Citation:
Aru V.,Sarais G.,Savorani F.,et al. Metabolic responses of clams, Ruditapes decussatus and Ruditapes philippinarum, to short-term exposure to lead and zinc[J]. Marine Pollution Bulletin,2016-01-01,107(1)