Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要:
A series of short-term toxicological tests were conducted on the rotifer Brachionus plicatilis to assess the toxicity of the flame retardant 2,2′,4,4′-tetrabrominated biphenyl ether (BDE-47). BDE-47 increased mortality, morphological damage, and altered population dynamics and fecundity of rotifer. Antioxidant enzymes were differentially changed to maintain the balance between antioxidant and pro-oxidant activity. However, with increases in the concentration of BDE-47, the metabolic and antioxidant activity decreased. Moreover, the reactive oxygen species (ROS) and malondialdehyde contents increased and the ratio between glutathione and glutathione-SH decreased, indicating oxidative stress. The addition of the ROS-inhibitor N-acetylcysteine alleviated the degree of damage and stimulated the activity of xenobiotic-metabolizing and antioxidant system, which suggested that ROS were the most important loop in the stress response. � 2017 Elsevier Ltd
College of Marine Life Sciences, Ocean University of China, Qingdao, Shandong Province, China; North China Sea Environmental Monitoring Center, State Oceanic Administration, Fushun Road 22, Qingdao, Shandong Province, China
Recommended Citation:
Jian X.,Tang X.,Xu N.,et al. Responses of the rotifer Brachionus plicatilis to flame retardant (BDE-47) stress[J]. Marine Pollution Bulletin,2017-01-01,116(2018-01-02)