| 项目编号: | 1701339
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| 项目名称: | Collaborative Research: Evaporation-Driven Optofluidic Biosensors using Photonic Crystal Biosilica |
| 作者: | Hua Tan
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| 承担单位: | Washington State University
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| 批准年: | 2017
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| 开始日期: | 2017-09-01
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| 结束日期: | 2020-08-31
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| 资助金额: | 100540
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | research
; research project
; summer research program
; optofluidic biosensor
; evaporation-induced
; nanophotonic technology
; diatom biosilica
; evaporation-induced capillary force
; diatom photonic crystal biosilica
; self-assembled three-dimensional photonic crystal
; evaporation-induced capillary flow
|
| 英文摘要: | The goal of this research project is to explore sensing of biological substances using naturally occurring diatoms, which are a group of single-celled algae found in nature that have been shown to possess unique properties suitable for biosensing applications. This research could lead to new methods to detect many types of biomolecules, which would in turn positively impact pollution monitoring, hazardous material detection, and early disease diagnosis. The integration of this research with education and outreach efforts benefits both graduate and undergraduate students at Oregon State University and Washington State University-Vancouver. Programmatic topics on nanophotonic technology and microfluidics are being added to curricula of these institutions, and efforts are underway to try to broaden the participation of under-represented minorities, women and K-12 students at these institutions through the summer research programs.
Evaporation-induced capillary flow in micro- and nano-scale structures can sustain a liquid flow without external pumps, and this can be a desirable feature for biosensing. The goal of this research project is to develop a new type of evaporation-driven, optofluidic biosensor using diatom photonic crystal biosilica. Diatoms are a group of single-celled photosynthetic algae that use biochemical pathways to biomineralize and self-assembled three-dimensional photonic crystals with unique photonic and micro- and nano-fluidic properties. Three aims are being pursued: 1) investigation of evaporation-induced capillary forces in the arrayed micro- and nanopores of diatom biosilica; 2) development of an optofluidic biosensor with enhanced light-matter interactions through in-pore plasmonic nanoparticles and 3) enabling a lab-on-chip optofluidic sensing system for trace level of biomarker detection, specifically for histamine as allergy biomarkers, using surface-enhanced Raman scattering (SERS) sensing. This research could lead to label-free sensing of many small biomolecules, which would positively impact pollution monitoring, hazardous material detection, and early disease diagnosis. The synergy of the research and education parts of this project benefits both graduate and undergraduate students at Oregon State University and Washington State University-Vancouver by enhancing their curricula with nanophotonic technology and microfluidics topics. The research project also has a component of broadening the participation of under-represented minorities, women and K-12 students through summer research programs. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/88926
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| Appears in Collections: | 全球变化的国际研究计划
科学计划与规划
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| Recommended Citation: | |
Hua Tan. Collaborative Research: Evaporation-Driven Optofluidic Biosensors using Photonic Crystal Biosilica. 2017-01-01.
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