| 项目编号: | 1600897
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| 项目名称: | DISSERTATION RESEARCH: The relative roles of selection and constraint in convergent ear loss across the true toads (Bufonidae) |
| 作者: | Kim Hoke
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| 承担单位: | Colorado State University
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| 批准年: | 2016
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| 开始日期: | 2016-06-01
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| 结束日期: | 2017-05-31
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| 资助金额: | 19630
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Biological Sciences - Environmental Biology
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| 英文关键词: | toad
; ear loss
; selection
; outer ear structure
; constraint
; outer ear development
; true toad
; selection pressure
; genetic constraint
; hearing sound
; convergent loss
; outer ear
; various selection pressure
; research team
; future research
; toad species
; ear structure evolution
; trait loss
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| 英文摘要: | Middle and outer ear structures are used for hearing sound and are shared by most land animals. Although frogs and toads use hearing to find a mate, many frogs and toads have lost their middle and outer ear structures. This project aims to discover the genetic changes that have resulted in the evolution of ear loss in toads. Since the middle and outer ears of other land animals (including humans) use similar developmental pathways, understanding the genetic changes that result in ear loss in toads will illuminate potential causes of middle and outer ear loss and malformation in other animals. The genetic data produced by this study will help us better understand the relationships between toad species and provide novel genetic data for future research. In addition to graduate training, interactive museum displays will be created from the specimens and data generated from the project, and a series of K-12 classroom exercises will be developed to explain the ear structure evolution in toads.
This project investigates the selection pressures and genetic constraints that generate convergent loss and potential regain of middle and outer ear structures across the family of true toads (Bufonidae). Sequence data for 60 bufonid species (16 earless, 44 eared) spanning seven ear loss events will be analyzed to identify signatures of selection and parallel genetic changes across 50 genes involved in middle and outer ear development. The dataset will assess the effects of various selection pressures and look for evidence of constraint at the genetic level, complementing the large amount of evidence for selection and constraint at the phenotypic level that has previously been collected by the research team. Results of this project will delineate the roles of selection and constraint in driving ear loss across Bufonidae, and elucidate common genetic pathways by which selection can act in a constrained, potentially costly, trait loss. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/92248
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| Appears in Collections: | 全球变化的国际研究计划
科学计划与规划
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| Recommended Citation: | |
Kim Hoke. DISSERTATION RESEARCH: The relative roles of selection and constraint in convergent ear loss across the true toads (Bufonidae). 2016-01-01.
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